Literature DB >> 20638636

Inflammasome inhibition as a pathogenic stealth mechanism.

Debra J Taxman1, Max T-H Huang, Jenny P-Y Ting.   

Abstract

The activation of inflammasomes containing NBD-LRR (NLRs) or non-NLRs is critical for effective host defense against microbial pathogens. Recent discoveries have uncovered a plethora of pathogenic strategies to inhibit inflammasome-mediated processing of IL-1beta and IL-18. We review recent evidence for viral and bacterial manipulation of the inflammasome, ranging from perturbation of caspase-1 activation to targeting of specific inflammasome components. Copyright 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20638636      PMCID： PMC2911019          DOI： 10.1016/j.chom.2010.06.005

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN： 1931-3128            Impact factor:   21.023


  29 in total

1.  A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system.

Authors:  Igor E Brodsky; Noah W Palm; Saheli Sadanand; Michelle B Ryndak; Fayyaz S Sutterwala; Richard A Flavell; James B Bliska; Ruslan Medzhitov
Journal:  Cell Host Microbe       Date:  2010-05-20       Impact factor: 21.023

Review 2.  Intracellular DNA recognition.

Authors:  Veit Hornung; Eicke Latz
Journal:  Nat Rev Immunol       Date:  2010-02       Impact factor: 53.106

3.  Characterization of the ectromelia virus serpin, SPI-2.

Authors:  Stephen J Turner; John Silke; Bronwyn Kenshole; Janet Ruby
Journal:  J Gen Virol       Date:  2000-10       Impact factor: 3.891

4.  Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo.

Authors:  Katrin D Mayer-Barber; Daniel L Barber; Kevin Shenderov; Sandra D White; Mark S Wilson; Allen Cheever; David Kugler; Sara Hieny; Patricia Caspar; Gabriel Núñez; Dirk Schlueter; Richard A Flavell; Fayyaz S Sutterwala; Alan Sher
Journal:  J Immunol       Date:  2010-03-03       Impact factor: 5.422

5.  Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of interleukin (IL)-1beta and IL-18.

Authors:  Ruth Cordoba-Rodriguez; Hui Fang; Carla S R Lankford; David M Frucht
Journal:  J Biol Chem       Date:  2004-03-09       Impact factor: 5.157

6.  Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms.

Authors:  Maya Saleh; John P Vaillancourt; Rona K Graham; Matthew Huyck; Srinivasa M Srinivasula; Emad S Alnemri; Martin H Steinberg; Vikki Nolan; Clinton T Baldwin; Richard S Hotchkiss; Timothy G Buchman; Barbara A Zehnbauer; Michael R Hayden; Lindsay A Farrer; Sophie Roy; Donald W Nicholson
Journal:  Nature       Date:  2004-05-06       Impact factor: 49.962

7.  Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.

Authors:  Hendrik Poeck; Michael Bscheider; Olaf Gross; Katrin Finger; Susanne Roth; Manuele Rebsamen; Nicole Hannesschläger; Martin Schlee; Simon Rothenfusser; Winfried Barchet; Hiroki Kato; Shizuo Akira; Satoshi Inoue; Stefan Endres; Christian Peschel; Gunther Hartmann; Veit Hornung; Jürgen Ruland
Journal:  Nat Immunol       Date:  2009-11-15       Impact factor: 25.606

8.  The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation.

Authors:  Christian Stehlik; Maryla Krajewska; Kate Welsh; Stanislaw Krajewski; Adam Godzik; John C Reed
Journal:  Biochem J       Date:  2003-07-01       Impact factor: 3.857

9.  The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells.

Authors:  J L Young; G K Sukhova; D Foster; W Kisiel; P Libby; U Schönbeck
Journal:  J Exp Med       Date:  2000-05-01       Impact factor: 14.307

10.  Co-regulation of NF-kappaB and inflammasome-mediated inflammatory responses by myxoma virus pyrin domain-containing protein M013.

Authors:  Masmudur M Rahman; Mohamed R Mohamed; Manbok Kim; Sherin Smallwood; Grant McFadden
Journal:  PLoS Pathog       Date:  2009-10-23       Impact factor: 6.823
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  55 in total

1.  The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.

Authors:  Takahito Sanada; Minsoo Kim; Hitomi Mimuro; Masato Suzuki; Michinaga Ogawa; Akiho Oyama; Hiroshi Ashida; Taira Kobayashi; Tomohiro Koyama; Shinya Nagai; Yuri Shibata; Jin Gohda; Jun-ichiro Inoue; Tsunehiro Mizushima; Chihiro Sasakawa
Journal:  Nature       Date:  2012-03-11       Impact factor: 49.962

Review 2.  Inflammasomes in health and disease.

Authors:  Till Strowig; Jorge Henao-Mejia; Eran Elinav; Richard Flavell
Journal:  Nature       Date:  2012-01-18       Impact factor: 49.962

3.  The protein SdhA maintains the integrity of the Legionella-containing vacuole.

Authors:  Elizabeth A Creasey; Ralph R Isberg
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-30       Impact factor: 11.205

Review 4.  Interleukin 1α and the inflammatory process.

Authors:  Nelson C Di Paolo; Dmitry M Shayakhmetov
Journal:  Nat Immunol       Date:  2016-07-19       Impact factor: 25.606

5.  Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis.

Authors:  Celine A Beamer; Benjamin P Seaver; David M Shepherd
Journal:  Toxicol Sci       Date:  2012-01-23       Impact factor: 4.849

Review 6.  The NLRP3 inflammasome in health and disease: the good, the bad and the ugly.

Authors:  P Menu; J E Vince
Journal:  Clin Exp Immunol       Date:  2011-07-15       Impact factor: 4.330

Review 7.  Immunogenic cell death in cancer and infectious disease.

Authors:  Lorenzo Galluzzi; Aitziber Buqué; Oliver Kepp; Laurence Zitvogel; Guido Kroemer
Journal:  Nat Rev Immunol       Date:  2016-10-17       Impact factor: 53.106

8.  Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin.

Authors:  Wei Li; Jingyi Yang; Ejuan Zhang; Maohua Zhong; Yang Xiao; Jie Yu; Dihan Zhou; Yuan Cao; Yi Yang; Yaoming Li; Huimin Yan
Journal:  Cell Mol Immunol       Date:  2015-04-27       Impact factor: 11.530

9.  Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis.

Authors:  Debra J Taxman; Karen V Swanson; Peter M Broglie; Haitao Wen; Elizabeth Holley-Guthrie; Max Tze-Han Huang; Justin B Callaway; Tim K Eitas; Joseph A Duncan; Jenny P Y Ting
Journal:  J Biol Chem       Date:  2012-07-26       Impact factor: 5.157

10.  YopM puts caspase-1 on ice.

Authors:  Ine Jørgensen; Edward A Miao
Journal:  Cell Host Microbe       Date:  2012-12-13       Impact factor: 21.023
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