Literature DB >> 20637815

Fibrin glue as a drug delivery system.

Patrick P Spicer1, Antonios G Mikos2.   

Abstract

Fibrin glue has been used surgically for decades for hemostasis as well as a sealant. It has also been researched as both a gel for cell delivery and a vehicle for drug delivery. The drug delivery applications for fibrin glue span tissue engineering to chemotherapy and involve several mechanisms for drug matrix interactions and control of release kinetics. Additionally, drugs or factors can be loaded in the gel via impregnation and tethering to the gel through covalent linkages or affinity-based systems. This review highlights recent research of fibrin glue as a drug delivery vehicle.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID： 20637815      PMCID： PMC3005546          DOI： 10.1016/j.jconrel.2010.06.025

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  56 in total

1.  Novel drug delivery system using autologous fibrin glue--release properties of anti-cancer drugs.

Authors:  H Yoshida; Y Yamaoka; M Shinoyama; A Kamiya
Journal:  Biol Pharm Bull       Date:  2000-03       Impact factor: 2.233

2.  Fibrin-based biomaterials to deliver human growth factors.

Authors:  Catalina Wong; Elisabeth Inman; Reiner Spaethe; Sam Helgerson
Journal:  Thromb Haemost       Date:  2003-03       Impact factor: 5.249

3.  Vascular endothelial growth factor binds to fibrinogen and fibrin and stimulates endothelial cell proliferation.

Authors:  A Sahni; C W Francis
Journal:  Blood       Date:  2000-12-01       Impact factor: 22.113

4.  Characterizing fibrin glue performance as modulated by heparin, aprotinin, and factor XIII.

Authors:  Gerard Marx; Xiaode Mou
Journal:  J Lab Clin Med       Date:  2002-09

5.  A novel method for gene delivery and expression in esophageal epithelium with fibrin glues containing replication-deficient adenovirus vector.

Authors:  F Teraishi; T Umeoka; T Saito; T Tsukagoshi; N Tanaka; T Fujiwara
Journal:  Surg Endosc       Date:  2003-11       Impact factor: 4.584

6.  Distribution and serum concentration of sisomicin released from fibrin glue-sealed dacron graft in the rat and human.

Authors:  T Osada; K Yamamura; K Yano; K Fujimoto; K Mizuno; T Sakurai; T Nabeshima
Journal:  J Biomed Mater Res       Date:  2000-10

7.  The S130K fibroblast growth factor-1 mutant induces heparin-independent proliferation and is resistant to thrombin degradation in fibrin glue.

Authors:  P K Shireman; L Xue; E Maddox; W H Burgess; H P Greisler
Journal:  J Vasc Surg       Date:  2000-02       Impact factor: 4.268

8.  Peripheral nerve grafts promoting central nervous system regeneration after spinal cord injury in the primate.

Authors:  Allan D O Levi; Hector Dancausse; Xiuming Li; Suzanne Duncan; Laura Horkey; Maria Oliviera
Journal:  J Neurosurg       Date:  2002-03       Impact factor: 5.115

9.  In vivo mesenchymal cell recruitment by a scaffold loaded with transforming growth factor beta1 and the potential for in situ chondrogenesis.

Authors:  Q Huang; J C H Goh; D W Hutmacher; E H Lee
Journal:  Tissue Eng       Date:  2002-07

10.  R136K fibroblast growth factor-1 mutant induces heparin-independent migration of endothelial cells through fibrin glue.

Authors:  Victor Z Erzurum; Jie-Fang Bian; Vicki A Husak; Joan Ellinger; Lian Xue; Wilson H Burgess; Howard P Greisler
Journal:  J Vasc Surg       Date:  2003-05       Impact factor: 4.268
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  39 in total

1.  A fibrin gel loaded with chitosan nanoparticles for local delivery of rhEGF: preparation and in vitro release studies.

Authors:  Wenjun Zhou; Min Zhao; Yuan Zhao; Yan Mou
Journal:  J Mater Sci Mater Med       Date:  2011-03-29       Impact factor: 3.896

2.  Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury.

Authors:  Oswald Steward; Kelli G Sharp; Kelly Matsudaira Yee; Maya N Hatch; Joseph F Bonner
Journal:  J Neurosci       Date:  2014-10-15       Impact factor: 6.167

3.  Harnessing endogenous stem/progenitor cells for tendon regeneration.

Authors:  Chang H Lee; Francis Y Lee; Solaiman Tarafder; Kristy Kao; Yena Jun; Guodong Yang; Jeremy J Mao
Journal:  J Clin Invest       Date:  2015-06-08       Impact factor: 14.808

4.  [Effects of different fibrin glue combination modes on the proliferation and viability of dental follicle cells].

Authors:  Liu Hong; Yang Chao; Chen Guoqing; Tian Weidong; Chen Yu
Journal:  Hua Xi Kou Qiang Yi Xue Za Zhi       Date:  2015-04

Review 5.  Controlled release strategies for bone, cartilage, and osteochondral engineering--Part II: challenges on the evolution from single to multiple bioactive factor delivery.

Authors:  Vítor E Santo; Manuela E Gomes; João F Mano; Rui L Reis
Journal:  Tissue Eng Part B Rev       Date:  2013-01-30       Impact factor: 6.389

6.  Structural basis for the nonlinear mechanics of fibrin networks under compression.

Authors:  Oleg V Kim; Rustem I Litvinov; John W Weisel; Mark S Alber
Journal:  Biomaterials       Date:  2014-05-16       Impact factor: 12.479

7.  Surgical Sutures with Porous Sheaths for the Sustained Release of Growth Factors.

Authors:  Jianhua Li; Stephen W Linderman; Chunlei Zhu; Hong Liu; Stavros Thomopoulos; Younan Xia
Journal:  Adv Mater       Date:  2016-04-05       Impact factor: 30.849

8.  Advancing biomaterials of human origin for tissue engineering.

Authors:  Fa-Ming Chen; Xiaohua Liu
Journal:  Prog Polym Sci       Date:  2015-03-28       Impact factor: 29.190

9.  Improvement in angiogenesis and osteogenesis with modified cannulated screws combined with VEGF/PLGA/fibrin glue in femoral neck fractures.

Authors:  Licheng Zhang; Lihai Zhang; Xia Lan; Meng Xu; Zhi Mao; Houchen Lv; Qi Yao; Peifu Tang
Journal:  J Mater Sci Mater Med       Date:  2014-01-17       Impact factor: 3.896

10.  Comprehensive evaluation of fibrin glue as a local drug-delivery system-efficacy and safety of sustained release of vancomycin by fibrin glue against local methicillin-resistant Staphylococcus aureus infection.

Authors:  Shinichi Ozaki; Aya Saito; Hidemasa Nakaminami; Minoru Ono; Norihisa Noguchi; Noboru Motomura
Journal:  J Artif Organs       Date:  2013-12-01       Impact factor: 1.731
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