SUMMARY OBJECTIVES: To evaluate the epidemiologic data of parasitic infections and co-infections in pregnant women in Lambaréné, Gabon. METHODS: In Lambaréné, Gabon--a region of high endemicity for Plasmodium falciparum and helminths--we conducted a longitudinal survey of malaria and helminth infections during pregnancy. RESULTS: Of 388 pregnant women included in the study, 98 (25%) experienced at least one episode of P. falciparum infection (incidence of 2.6 infections per year of pregnancy). One hundred and seventy pregnant women (49%) were infected with intestinal helminths, and 41 (12%) harboured Shistosoma haematobium. In total, 230 (65%) pregnant women carried at least one parasitic infection are 74 (22%) harboured at least two or more parasite species. Ascaris lumbricoides and primiparity were independently associated with Plasmodium infection during pregnancy [odds ratio (95% confidence intervals) 2.4, (1.4-3.8); 2.1, (1.3-3.5), respectively]. CONCLUSION: This study shows a high burden of parasitic infections with substantial degree of parasitic co-infections in pregnant women in a Central African region. This may have implications for immunological studies and operational research involving pregnant women.
SUMMARY OBJECTIVES: To evaluate the epidemiologic data of parasitic infections and co-infections in pregnant women in Lambaréné, Gabon. METHODS: In Lambaréné, Gabon--a region of high endemicity for Plasmodium falciparum and helminths--we conducted a longitudinal survey of malaria and helminth infections during pregnancy. RESULTS: Of 388 pregnant women included in the study, 98 (25%) experienced at least one episode of P. falciparum infection (incidence of 2.6 infections per year of pregnancy). One hundred and seventy pregnant women (49%) were infected with intestinal helminths, and 41 (12%) harboured Shistosoma haematobium. In total, 230 (65%) pregnant women carried at least one parasitic infection are 74 (22%) harboured at least two or more parasite species. Ascaris lumbricoides and primiparity were independently associated with Plasmodiuminfection during pregnancy [odds ratio (95% confidence intervals) 2.4, (1.4-3.8); 2.1, (1.3-3.5), respectively]. CONCLUSION: This study shows a high burden of parasitic infections with substantial degree of parasitic co-infections in pregnant women in a Central African region. This may have implications for immunological studies and operational research involving pregnant women.
Authors: Ayola A Adegnika; Adrian J F Luty; Martin P Grobusch; Michael Ramharter; Maria Yazdanbakhsh; Peter G Kremsner; Norbert G Schwarz Journal: Malar J Date: 2011-04-22 Impact factor: 2.979
Authors: Doris González-Fernández; Kristine G Koski; Odalis Teresa Sinisterra; Emérita Del Carmen Pons; Enrique Murillo; Marilyn E Scott Journal: Am J Trop Med Hyg Date: 2015-03-30 Impact factor: 2.345
Authors: Amy S Anderson; Benjamin C Trumble; Carmen Hové; Thomas S Kraft; Hillard Kaplan; Michael Gurven; Aaron D Blackwell Journal: Am J Hum Biol Date: 2019-10-23 Impact factor: 1.937
Authors: Odilon Nouatin; Ulysse Ateba Ngoa; Javier Ibáñez; Jean Claude Dejon-Agobe; Benjamin Mordmüller; Jean Ronald Edoa; Fabrice Mougeni; Sina Brückner; Aurore Bouyoukou Hounkpatin; Meral Esen; Michael Theisen; Kabirou Moutairou; Stephen L Hoffman; Saadou Issifou; Adrian J F Luty; Marguerite M Loembe; Selidji Todagbé Agnandji; Bertrand Lell; Peter G Kremsner; Ayôla Akim Adegnika Journal: Vaccine Date: 2020-05-05 Impact factor: 3.641
Authors: Jessica K Fairley; Donal Bisanzio; Charles H King; Uriel Kitron; Peter Mungai; Eric Muchiri; Christopher L King; Indu Malhotra Journal: Am J Trop Med Hyg Date: 2012-11-19 Impact factor: 2.345
Authors: Ayola A Adegnika; Jeannot F Zinsou; Saadou Issifou; Ulysse Ateba-Ngoa; Roland F Kassa; Eliane N Feugap; Yabo J Honkpehedji; Jean-Claude Dejon Agobe; Hilaire M Kenguele; Marguerite Massinga-Loembe; Selidji T Agnandji; Benjamin Mordmüller; Michael Ramharter; Maria Yazdanbakhsh; Peter G Kremsner; Bertrand Lell Journal: Antimicrob Agents Chemother Date: 2014-02-18 Impact factor: 5.191
Authors: Kevin C Kobylinski; Haoues Alout; Brian D Foy; Archie Clements; Poom Adisakwattana; Brett E Swierczewski; Jason H Richardson Journal: Am J Trop Med Hyg Date: 2014-07-28 Impact factor: 2.345