| Literature DB >> 20636085 |
Ivar Meyvantsson1, David J Beebe.
Abstract
Microfluidic technology holds great promise for the creation of advanced cell culture models. In this review, we discuss the characterization of cell culture in microfluidic systems, describe important biochemical and physical features of the cell microenvironment, and review studies of microfluidic cell manipulation in the context of these features. Finally, we consider the integration of analytical elements, ways to achieve high throughput, and the design constraints imposed by cell biology applications.Mesh:
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Year: 2008 PMID: 20636085 DOI: 10.1146/annurev.anchem.1.031207.113042
Source DB: PubMed Journal: Annu Rev Anal Chem (Palo Alto Calif) ISSN: 1936-1327 Impact factor: 10.745