| Literature DB >> 20635168 |
Lihua Zhao1, Yanhui Sun, Xiaoqing Li, Xianqing Jin, Youhua Xu, Zhenhua Guo, Rui Liang, Xionghui Ding, Tingfu Chen, Siqi Wang.
Abstract
The novel gene HA117 is a multidrug resistance (MDR) gene in all-trans retinoic acid resistance HL-60 cells. The transduction of adenovirus vectors encoding HA117 conferred breast cancer cell line 4T1 MDR not only to MRP1 substrate drugs but also to MRP1 non-substrate drugs and the MDR strength of HA117 was similar to that of multidrug resistance-associated protein-1 (MRP1) for MRP1 substrate, but HA117 had no daunorubicin-excretion function.Entities:
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Year: 2010 PMID： 20635168 DOI： 10.1007/s12032-010-9624-y
Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064