Literature DB >> 20634805

Vive la science! Vive le hérisson!

Jeremy F Reiter1, Frederic J de Sauvage.   

Abstract

The EMBO workshop 'Hedgehog Signalling: from Developmental Biology to Anti-cancer Drugs' took place between 27 and 31 March on the beautiful Côte d'Azur. The gathered scientists tackled topics ranging from the mechanisms by which Hedgehog (Hh) is presented to receptive cells, to the distribution of Hh by Glypicans, to the role of cilia in vertebrate Hh signal transduction, and to the function of Hh signals in cancer.

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Year:  2010        PMID： 20634805      PMCID： PMC2920439          DOI： 10.1038/embor.2010.109

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


  12 in total

1.  Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs.

Authors:  F A Ramírez-Weber; T B Kornberg
Journal:  Cell       Date:  1999-05-28       Impact factor: 41.582

2.  The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum.

Authors:  Katie L Ayers; Armel Gallet; Laurence Staccini-Lavenant; Pascal P Thérond
Journal:  Dev Cell       Date:  2010-04-20       Impact factor: 12.270

3.  Lipoprotein particles are required for Hedgehog and Wingless signalling.

Authors:  Daniela Panáková; Hein Sprong; Eric Marois; Christoph Thiele; Suzanne Eaton
Journal:  Nature       Date:  2005-05-05       Impact factor: 49.962

4.  Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

Authors:  Viljar Jaks; Nick Barker; Maria Kasper; Johan H van Es; Hugo J Snippert; Hans Clevers; Rune Toftgård
Journal:  Nat Genet       Date:  2008-10-12       Impact factor: 38.330

5.  Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells.

Authors:  R Burke; D Nellen; M Bellotto; E Hafen; K A Senti; B J Dickson; K Basler
Journal:  Cell       Date:  1999-12-23       Impact factor: 41.582

6.  Evidence for a role of vertebrate Disp1 in long-range Shh signaling.

Authors:  L Alton Etheridge; T Quinn Crawford; Shile Zhang; Henk Roelink
Journal:  Development       Date:  2010-01       Impact factor: 6.868

7.  A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway.

Authors:  Kent Nybakken; Steven A Vokes; Ting-Yi Lin; Andrew P McMahon; Norbert Perrimon
Journal:  Nat Genet       Date:  2005-11-20       Impact factor: 38.330

8.  Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.

Authors:  Gianluca Canettieri; Lucia Di Marcotullio; Azzura Greco; Sonia Coni; Laura Antonucci; Paola Infante; Laura Pietrosanti; Enrico De Smaele; Elisabetta Ferretti; Evelina Miele; Marianna Pelloni; Giuseppina De Simone; Emilia Maria Pedone; Paola Gallinari; Alessandra Giorgi; Christian Steinkühler; Luigi Vitagliano; Carlo Pedone; M Eugenià Schinin; Isabella Screpanti; Alberto Gulino
Journal:  Nat Cell Biol       Date:  2010-01-17       Impact factor: 28.824

9.  Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449.

Authors:  Charles M Rudin; Christine L Hann; John Laterra; Robert L Yauch; Christopher A Callahan; Ling Fu; Thomas Holcomb; Jeremy Stinson; Stephen E Gould; Barbara Coleman; Patricia M LoRusso; Daniel D Von Hoff; Frederic J de Sauvage; Jennifer A Low
Journal:  N Engl J Med       Date:  2009-09-02       Impact factor: 91.245

10.  Inhibition of the hedgehog pathway in advanced basal-cell carcinoma.

Authors:  Daniel D Von Hoff; Patricia M LoRusso; Charles M Rudin; Josina C Reddy; Robert L Yauch; Raoul Tibes; Glen J Weiss; Mitesh J Borad; Christine L Hann; Julie R Brahmer; Howard M Mackey; Bertram L Lum; Walter C Darbonne; James C Marsters; Frederic J de Sauvage; Jennifer A Low
Journal:  N Engl J Med       Date:  2009-09-02       Impact factor: 91.245
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