Literature DB >> 206347

EBV-related cytotoxicity of Fc receptor negative T lymphocytes separated from the blood of infectious mononucleosis patients.

T Bakacs, E Svedmyr, E Klein.   

Abstract

Epstein-Barr virus (EBV) related specific killing was demonstrated previously in the T cell enriched subpopulations of blood lymphocytes of IM patients. In the present work we demonstrate that the cytotoxic cells belong to the Fc negative T subset. T cells in the blood of IM patients can be divided in 2 categories, 1 Fc positive with non discriminative cytotoxicity and the other, Fc negative with selective cytotoxicity against EBV genome carrying lymphoblastoid cell lines.

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Year:  1978        PMID: 206347     DOI: 10.1016/s0304-3835(78)94347-1

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  6 in total

1.  In vitro expansion of Epstein-Barr virus-specific HLA-restricted cytotoxic T cells direct from the blood of infectious mononucleosis patients.

Authors:  G Strang; A B Rickinson
Journal:  Immunology       Date:  1987-12       Impact factor: 7.397

Review 2.  Clinical consequences of Epstein-Barr virus infection and possible control by an anti-viral vaccine.

Authors:  M A Epstein; A J Morgan
Journal:  Clin Exp Immunol       Date:  1983-08       Impact factor: 4.330

3.  Lymphoma development in mice and humans: diversity of initiation is followed by convergent cytogenetic evolution.

Authors:  G Klein
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

4.  Cytotoxic effector cells from infectious mononucleosis patients in the acute phase do not specifically kill Epstein-Barr virus genome-carrying lymphoid cell lines.

Authors:  P C Patel; G Dorval; J Menezes
Journal:  Infect Immun       Date:  1982-10       Impact factor: 3.441

5.  Target selectivity of interferon-induced human killer lymphocytes related to their Fc receptor expression.

Authors:  M G Masucci; G Masucci; E Klein; W Berthold
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

6.  Absence of allogeneic restriction in human T-cell-mediated cytotoxicity to Epstein-Barr virus-infected target cells. Demonstration of an HLA-linked control at the effector level.

Authors:  M Lipinski; W H Fridman; T Tursz; C Vincent; D Pious; M Fellous
Journal:  J Exp Med       Date:  1979-12-01       Impact factor: 14.307

  6 in total

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