Lactic dehydrogenase and glycolytic activity of human platelets in uncomplicated pregnancy.

Lactic dehydrogenase (LDH) of isolated platelets was determined in a group of 103 normally pregnant and 19 unpregnant women. LDH activity is significantly increased in the last trimester of pregnancy while the isoenzyme pattern does not vary in relation to LDH increase. Moreover, glucose consumption and lactic acid production are linearly correlated to platelet LDH activity.