Literature DB >> 20632813

How paraproteins can affect laboratory assays: spurious results and biological effects.

Richard I King1, Christopher M Florkowski.   

Abstract

The presence of large amounts of monoclonal paraprotein in the serum can lead to a range of spurious laboratory results. These may result from analytical interference of the M-protein through chemical or immunological means, or from pre-analytical interference; the different modes of interference are explored in this review along with suggested methods of prevention or detection.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20632813     DOI： 10.3109/00313025.2010.493868

Source DB:  PubMed          Journal:  Pathology        ISSN： 0031-3025            Impact factor:   5.306


  8 in total

1.  A suspected case of falsely low digoxin and vancomycin concentrations caused by free kappa light chains with PETINIA method.

Authors:  Nga Yeung Tang; Kelly Walewski; Robin Carey-Ballough; Elizabeth Sykes; Qian Sun
Journal:  Pract Lab Med       Date:  2022-04-28

2.  A component could not be larger than the whole, polyclonal immunoglobulin interference in conjugated/direct bilirubin assay and elimination: A case report.

Authors:  Neda Soleimani; Saeideh Khaleghpanah; Sahand Mohammadzadeh
Journal:  Clin Case Rep       Date:  2022-05-15

Review 3.  Practical Considerations for the Use of Daratumumab, a Novel CD38 Monoclonal Antibody, in Myeloma.

Authors:  Philippe Moreau; Niels W C J van de Donk; Jesus San Miguel; Henk Lokhorst; Hareth Nahi; Dina Ben-Yehuda; Michele Cavo; Gordon Cook; Michel Delforge; Hermann Einsele; Sonja Zweegman; Heinz Ludwig; Christoph Driessen; Antonio Palumbo; Thierry Facon; Torben Plesner; Meletios Dimopoulos; Pia Sondergeld; Pieter Sonneveld; María-Victoria Mateos
Journal:  Drugs       Date:  2016-05       Impact factor: 9.546

4.  The pH of chemistry assays plays an important role in monoclonal immunoglobulin interferences.

Authors:  Michael O Alberti; Thomas A Drake; Lu Song
Journal:  Pract Lab Med       Date:  2015-10-09

5.  Pre-analytical mysteries: A case of severe hypervitaminosis D and mild hypercalcaemia.

Authors:  Emma Whittle; Elzahn de Waal; Tony Huynh; Oliver Treacy; Adam Morton
Journal:  Biochem Med (Zagreb)       Date:  2020-12-15       Impact factor: 2.313

6.  Evaluation of SARS-CoV-2 Serological Testing in Patients with Multiple Myeloma and Other Hematologic Malignancies on Monoclonal Antibody Therapies.

Authors:  Lenin Mahimainathan; Madhusudhanan Narasimhan; Rolando Corchado; Hetalkumari Patel; Ankit Kansagra; Sridevi Devaraj; Praveen Ramakrishnan Geethakumari; Alagarraju Muthukumar
Journal:  Diagnostics (Basel)       Date:  2020-11-24

7.  Cystatin C-Based Equations Detect Hidden Kidney Disease and Poor Prognosis in Newly Diagnosed Patients with Multiple Myeloma.

Authors:  Francisco-Javier Cepeda-Piorno; Esther González-García; Alba Méndez-Gallego; Juan Torres-Varona; Vanesa García-Moreira; Christian Sordo-Bahamonde; Cristina AlberdiGarcía-Del-Castillo; Elene Astobieta-Madariaga; Maria-Victoria Mateos-Manteca; Segundo González-Rodríguez
Journal:  Adv Hematol       Date:  2022-04-16

8.  Interference of M-protein on prothrombin time test - case report.

Authors:  Sandra Margetić; Ivana Ćelap; Lora Dukić; Ines Vukasović; Lucija Virović-Jukić
Journal:  Biochem Med (Zagreb)       Date:  2016       Impact factor: 2.313
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.