Literature DB >> 20632802

Human herpesvirus-6 entry into host cells.

Huamin Tang1, Yasuko Mori.   

Abstract

Human herpesvirus-6 (HHV-6) belongs to the herpesvirus family and is categorized into variant A and B (HHV-6A and HHV-6B). Primary HHV-6 infection in children and its related diseases are almost exclusively caused by HHV-6B and no disease caused by HHV-6A has been identified. The cellular receptor of HHV-6 has been shown to be a human CD46, and its viral ligand is an envelope glycoprotein complex, gH/gL/gQ1/gQ2 in HHV-6A. Furthermore, both cellular and viral lipid rafts play an important role in the HHV-6 entry process, suggesting that HHV-6 may enter its target cells through a lipid raft-associated mechanism.

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Year:  2010        PMID: 20632802     DOI: 10.2217/fmb.10.61

Source DB:  PubMed          Journal:  Future Microbiol        ISSN: 1746-0913            Impact factor:   3.165


  13 in total

Review 1.  Annexins as organizers of cholesterol- and sphingomyelin-enriched membrane microdomains in Niemann-Pick type C disease.

Authors:  Magdalena Domon; Mehmet Nail Nasir; Gladys Matar; Slawomir Pikula; Françoise Besson; Joanna Bandorowicz-Pikula
Journal:  Cell Mol Life Sci       Date:  2011-12-13       Impact factor: 9.261

2.  Analysis of a neutralizing antibody for human herpesvirus 6B reveals a role for glycoprotein Q1 in viral entry.

Authors:  Akiko Kawabata; Hiroko Oyaizu; Takahiro Maeki; Huamin Tang; Koichi Yamanishi; Yasuko Mori
Journal:  J Virol       Date:  2011-09-28       Impact factor: 5.103

Review 3.  The roles of viruses in brain tumor initiation and oncomodulation.

Authors:  Alexander Kofman; Lucasz Marcinkiewicz; Evan Dupart; Anton Lyshchev; Boris Martynov; Anatolii Ryndin; Elena Kotelevskaya; Jay Brown; David Schiff; Roger Abounader
Journal:  J Neurooncol       Date:  2011-07-01       Impact factor: 4.130

4.  Entry of Classical Swine Fever Virus into PK-15 Cells via a pH-, Dynamin-, and Cholesterol-Dependent, Clathrin-Mediated Endocytic Pathway That Requires Rab5 and Rab7.

Authors:  Bao-Jun Shi; Chun-Chun Liu; Jing Zhou; Shi-Qi Wang; Zhi-Can Gao; Xiao-Min Zhang; Bin Zhou; Pu-Yan Chen
Journal:  J Virol       Date:  2016-09-29       Impact factor: 5.103

5.  Cell Surface THY-1 Contributes to Human Cytomegalovirus Entry via a Macropinocytosis-Like Process.

Authors:  Qingxue Li; Elizabeth Fischer; Jeffrey I Cohen
Journal:  J Virol       Date:  2016-10-14       Impact factor: 5.103

6.  Maturation of human herpesvirus 6A glycoprotein O requires coexpression of glycoprotein H and glycoprotein L.

Authors:  Huamin Tang; Nora F Mahmoud; Yasuko Mori
Journal:  J Virol       Date:  2015-02-18       Impact factor: 5.103

7.  Human herpesvirus 6 glycoprotein complex formation is required for folding and trafficking of the gH/gL/gQ1/gQ2 complex and its cellular receptor binding.

Authors:  Huamin Tang; Mayuko Hayashi; Takahiro Maeki; Koichi Yamanishi; Yasuko Mori
Journal:  J Virol       Date:  2011-08-17       Impact factor: 5.103

8.  Determinants of Human CD134 Essential for Entry of Human Herpesvirus 6B.

Authors:  Huamin Tang; Yasuko Mori
Journal:  J Virol       Date:  2015-07-22       Impact factor: 5.103

Review 9.  Classification of HHV-6A and HHV-6B as distinct viruses.

Authors:  Dharam Ablashi; Henri Agut; Roberto Alvarez-Lafuente; Duncan A Clark; Stephen Dewhurst; Dario DiLuca; Louis Flamand; Niza Frenkel; Robert Gallo; Ursula A Gompels; Per Höllsberg; Steven Jacobson; Mario Luppi; Paolo Lusso; Mauro Malnati; Peter Medveczky; Yasuko Mori; Philip E Pellett; Joshua C Pritchett; Koichi Yamanishi; Tetsushi Yoshikawa
Journal:  Arch Virol       Date:  2013-11-06       Impact factor: 2.574

Review 10.  Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.

Authors:  Sabrina M de Munnik; Martine J Smit; Rob Leurs; Henry F Vischer
Journal:  Front Pharmacol       Date:  2015-03-09       Impact factor: 5.810

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