BACKGROUND: Bilateral superficial cervical block during thyroid surgery can reduce postoperative pain but its value is unclear. This randomized clinical trial assessed the efficacy of such regional anaesthesia on postoperative painafter thyroid surgery performed under general anaesthesia. METHODS:Patients undergoing thyroid surgery were randomized to one of four groups in a double-blind fashion. Patients received a cervical block with placebo or bupivacaine at the start or end of surgery. Postoperative pain, analgesic use and length of hospital stay were assessed. RESULTS: There were 159 patients eligible for analysis. The bupivacaine group had significantly less pain than the placebo group (P = 0.016). The timing of bupivacaine administration did not significantly influence pain (preoperative versus postoperative, P = 0.723). There was no difference between groups in the amount of analgesic used. Length of hospital stay was the same in the bupivacaine and placebo groups (P = 0.925) and when bupivacaine was administered at the beginning or end of surgery (P = 0.087). CONCLUSION: Bilateral superficial cervical block with bupivacaine combined with general anaesthesia significantly reduced postoperative painafter thyroid surgery. REGISTRATION NUMBER: NCT00472446 (http://www.clinicaltrials.gov). Copyright (c) 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. Copyright2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
RCT Entities:
BACKGROUND: Bilateral superficial cervical block during thyroid surgery can reduce postoperative pain but its value is unclear. This randomized clinical trial assessed the efficacy of such regional anaesthesia on postoperative pain after thyroid surgery performed under general anaesthesia. METHODS:Patients undergoing thyroid surgery were randomized to one of four groups in a double-blind fashion. Patients received a cervical block with placebo or bupivacaine at the start or end of surgery. Postoperative pain, analgesic use and length of hospital stay were assessed. RESULTS: There were 159 patients eligible for analysis. The bupivacaine group had significantly less pain than the placebo group (P = 0.016). The timing of bupivacaine administration did not significantly influence pain (preoperative versus postoperative, P = 0.723). There was no difference between groups in the amount of analgesic used. Length of hospital stay was the same in the bupivacaine and placebo groups (P = 0.925) and when bupivacaine was administered at the beginning or end of surgery (P = 0.087). CONCLUSION: Bilateral superficial cervical block with bupivacaine combined with general anaesthesia significantly reduced postoperative pain after thyroid surgery. REGISTRATION NUMBER: NCT00472446 (http://www.clinicaltrials.gov). Copyright (c) 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. Copyright 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Authors: Ali Ahiskalioglu; Ahmet Murat Yayik; Elif Oral Ahiskalioglu; Aysenur Dostbil; Omer Doymus; Erdem Karadeniz; Muhammet Ali Ari; Furkan Sengoz; Haci Ahmet Alici; Erkan Cem Celik Journal: J Anesth Date: 2018-02-21 Impact factor: 2.078
Authors: Ignazio Tarantino; Ulrich Beutner; Walter Kolb; Sascha A Müller; Cornelia Lüthi; Andreas Lüthi; Bruno M Schmied; Thomas Clerici; Rene Warschkow Journal: BMC Anesthesiol Date: 2013-09-09 Impact factor: 2.217