Literature DB >> 20632025

Severe encephalopathy and polyneuropathy induced by dichloroacetate.

Dieta Brandsma, Thomas P C Dorlo, John H Haanen, Jos H Beijnen, Willem Boogerd.   

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Year:  2010        PMID： 20632025     DOI： 10.1007/s00415-010-5654-9

Source DB:  PubMed          Journal:  J Neurol        ISSN： 0340-5354            Impact factor:   4.849


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  6 in total

1.  A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.

Authors:  Sébastien Bonnet; Stephen L Archer; Joan Allalunis-Turner; Alois Haromy; Christian Beaulieu; Richard Thompson; Christopher T Lee; Gary D Lopaschuk; Lakshmi Puttagunta; Sandra Bonnet; Gwyneth Harry; Kyoko Hashimoto; Christopher J Porter; Miguel A Andrade; Bernard Thebaud; Evangelos D Michelakis
Journal:  Cancer Cell       Date:  2007-01       Impact factor: 31.743

2.  Metabolic modulation of glioblastoma with dichloroacetate.

Authors:  E D Michelakis; G Sutendra; P Dromparis; L Webster; A Haromy; E Niven; C Maguire; T-L Gammer; J R Mackey; D Fulton; B Abdulkarim; M S McMurtry; K C Petruk
Journal:  Sci Transl Med       Date:  2010-05-12       Impact factor: 17.956

3.  Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children.

Authors:  Peter W Stacpoole; Douglas S Kerr; Carie Barnes; S Terri Bunch; Paul R Carney; Eileen M Fennell; Natalia M Felitsyn; Robin L Gilmore; Melvin Greer; George N Henderson; Alan D Hutson; Richard E Neiberger; Ralph G O'Brien; Leigh Ann Perkins; Ronald G Quisling; Albert L Shroads; Jonathan J Shuster; Janet H Silverstein; Douglas W Theriaque; Edward Valenstein
Journal:  Pediatrics       Date:  2006-05       Impact factor: 7.124

4.  Age-dependent kinetics and metabolism of dichloroacetate: possible relevance to toxicity.

Authors:  Albert L Shroads; Xu Guo; Vaishali Dixit; Hui-Ping Liu; Margaret O James; Peter W Stacpoole
Journal:  J Pharmacol Exp Ther       Date:  2007-12-20       Impact factor: 4.030

5.  Dichloroacetate causes toxic neuropathy in MELAS: a randomized, controlled clinical trial.

Authors:  P Kaufmann; K Engelstad; Y Wei; S Jhung; M C Sano; D C Shungu; W S Millar; X Hong; C L Gooch; X Mao; J M Pascual; M Hirano; P W Stacpoole; S DiMauro; D C De Vivo
Journal:  Neurology       Date:  2006-02-14       Impact factor: 9.910

Review 6.  Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer.

Authors:  E D Michelakis; L Webster; J R Mackey
Journal:  Br J Cancer       Date:  2008-09-02       Impact factor: 7.640
  6 in total
  8 in total

1.  Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site.

Authors:  Tiziana Masini; Barbara Birkaya; Simon van Dijk; Milon Mondal; Johan Hekelaar; Manuel Jäger; Anke C Terwisscha van Scheltinga; Mulchand S Patel; Anna K H Hirsch; Edelmiro Moman
Journal:  J Enzyme Inhib Med Chem       Date:  2016-07-19       Impact factor: 5.051

Review 2.  SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms.

Authors:  Yangzom D Bhutia; Ellappan Babu; Sabarish Ramachandran; Shengping Yang; Muthusamy Thangaraju; Vadivel Ganapathy
Journal:  Biochem J       Date:  2016-05-01       Impact factor: 3.857

3.  Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate.

Authors:  E Babu; S Ramachandran; V CoothanKandaswamy; S Elangovan; P D Prasad; V Ganapathy; M Thangaraju
Journal:  Oncogene       Date:  2011-04-18       Impact factor: 9.867

4.  The proline regulatory axis and cancer.

Authors:  James Ming Phang; Wei Liu; Chad Hancock; Kyle J Christian
Journal:  Front Oncol       Date:  2012-06-21       Impact factor: 6.244

5.  Long-term stabilization of stage 4 colon cancer using sodium dichloroacetate therapy.

Authors:  Akbar Khan; Douglas Andrews; Anneke C Blackburn
Journal:  World J Clin Cases       Date:  2016-10-16       Impact factor: 1.337

6.  Long-term stabilization of metastatic melanoma with sodium dichloroacetate.

Authors:  Akbar Khan; Doug Andrews; Jill Shainhouse; Anneke C Blackburn
Journal:  World J Clin Oncol       Date:  2017-08-10

7.  The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism.

Authors:  Nerea Allende-Vega; Ewelina Krzywinska; Stefania Orecchioni; Nuria Lopez-Royuela; Francesca Reggiani; Giovanna Talarico; Jean-François Rossi; Rodrigue Rossignol; Yosr Hicheri; Guillaume Cartron; Francesco Bertolini; Martin Villalba
Journal:  Oncotarget       Date:  2015-08-07

Review 8.  Dichloroacetate (DCA) and Cancer: An Overview towards Clinical Applications.

Authors:  Tiziana Tataranni; Claudia Piccoli
Journal:  Oxid Med Cell Longev       Date:  2019-11-14       Impact factor: 6.543
  8 in total

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