Literature DB >> 20631333

Utility of pandemic H1N1 2009 influenza virus recombinant hemagglutinin protein-based enzyme-linked immunosorbent assay for serosurveillance.

V A Arankalle1, R G Virkar, B V Tandale, N B Ingle.   

Abstract

An enzyme-linked immunosorbent assay (ELISA) for the detection of IgG antibodies against the pandemic H1N1 2009 influenza A virus, employing a recombinant hemagglutinin protein of the virus, was compared to the hemagglutination inhibition (HI) test using 783 serum samples. The results showed a concordance of 98.4%, suggesting the utility of the ELISA in serosurveillance. Two hundred sixty-nine (100%) serum samples with an HI titer of > or =20 were ELISA reactive.

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Year:  2010        PMID： 20631333      PMCID： PMC2944451          DOI： 10.1128/CVI.00223-10

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


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