Literature DB >> 20631106

Clinical utility of genotypic resistance tests for HIV-1-infected patients with low-level virological failure.

A Elgalib1, M Perry, M Aboud, J Mullen, S O'Shea, I L Chrystie, R Kulasegaram, C Y W Tong.   

Abstract

The usefulness of genotypic resistance tests (GRT) among HIV-1 patients with low-level virological failure (LLVF) was evaluated. Up to 78% of samples with <1,000 copies/ml were sequenced successfully. For samples with 50 to 200 copies/ml, the success rate was as high as 69%. LLVF should not deter clinicians from requesting GRT.

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Year:  2010        PMID： 20631106      PMCID： PMC2937687          DOI： 10.1128/JCM.01335-10

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  8 in total

1.  Detection of HIV-1 antiretroviral resistance from patients with persistently low but detectable viraemia.

Authors:  Nicola Mackie; Simon Dustan; Myra O McClure; Jonathan N Weber; John R Clarke
Journal:  J Virol Methods       Date:  2004-08       Impact factor: 2.014

2.  HIV-1 drug resistance genotype results in patients with plasma samples with HIV-1 RNA levels less than 75 copies/mL.

Authors:  Yumi Mitsuya; Mark A Winters; W Jeffrey Fessel; Soo-Yon Rhee; Sally Slome; Jason Flamm; Michael Horberg; Leo Hurley; Daniel Klein; Robert W Shafer
Journal:  J Acquir Immune Defic Syndr       Date:  2006-09       Impact factor: 3.731

3.  Successful use of genotypic resistance testing in HIV-1-infected individuals with detectable viraemia between 50 and 1000 copies/ml.

Authors:  Laura Waters; S Mandalia; David Asboe
Journal:  AIDS       Date:  2006-03-21       Impact factor: 4.177

4.  Detection of drug resistance mutations as a predictor of subsequent virological failure in patients with HIV-1 viral rebounds of less than 1,000 RNA copies/ml.

Authors:  Chris Verhofstede; Filip Van Wanzeele; Bea Van Der Gucht; Jolanda Pelgrom; Linos Vandekerckhove; Jean Plum; Dirk Vogelaers
Journal:  J Med Virol       Date:  2007-09       Impact factor: 2.327

5.  British HIV Association Guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008.

Authors:  B G Gazzard; Jane Anderson; Abdel Babiker; Marta Boffito; Gary Brook; Gary Brough; Duncan Churchill; Ben Cromarty; Satyajit Das; Martin Fisher; Andrew Freedman; Anna Maria Geretti; Margaret Johnson; Saye Khoo; Clifford Leen; Devaki Nair; Barry Peters; Andrew Phillips; Deenan Pillay; Anton Pozniak; John Walsh; Ed Wilkins; Ian Williams; Matthew Williams; Mike Youle
Journal:  HIV Med       Date:  2008-10       Impact factor: 3.180

6.  Genotyping of B and non-B subtypes of human immunodeficiency virus type 1.

Authors:  C Y W Tong; J Mullen; R Kulasegaram; A De Ruiter; S O'Shea; I L Chrystie
Journal:  J Clin Microbiol       Date:  2005-09       Impact factor: 5.948

7.  Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel.

Authors:  Scott M Hammer; Joseph J Eron; Peter Reiss; Robert T Schooley; Melanie A Thompson; Sharon Walmsley; Pedro Cahn; Margaret A Fischl; Jose M Gatell; Martin S Hirsch; Donna M Jacobsen; Julio S G Montaner; Douglas D Richman; Patrick G Yeni; Paul A Volberding
Journal:  JAMA       Date:  2008-08-06       Impact factor: 56.272

8.  European AIDS Clinical Society (EACS) guidelines for the clinical management and treatment of HIV-infected adults.

Authors:  N Clumeck; A Pozniak; F Raffi
Journal:  HIV Med       Date:  2008-02       Impact factor: 3.180
  8 in total
  1 in total

Review 1.  Current practices in laboratory monitoring of HIV infection.

Authors:  Madhu Vajpayee; Teena Mohan
Journal:  Indian J Med Res       Date:  2011-12       Impact factor: 2.375
  1 in total

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