Literature DB >> 20630771

Molecular and cellular basis of T cell lineage commitment.

Rita Vicente1, Louise Swainson, Sophie Marty-Grès, Stéphanie C De Barros, Sandrina Kinet, Valérie S Zimmermann, Naomi Taylor.   

Abstract

The thymus forms as an alymphoid thymic primordium with T cell differentiation requiring the seeding of this anlage. This review will focus on the characteristics of the hematopoietic progenitors which colonize the thymus and their subsequent commitment/differentiation, both in mice and men. Within the thymus, the interplay between Notch1 and IL-7 signals is crucial for the orchestration of T cell development, but the precise requirements for these factors in murine and human thympoeisis are not synonymous. Recent advances in our understanding of the mechanisms regulating precursor entry and their maintenance in the thymus will also be presented. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20630771      PMCID: PMC2992869          DOI: 10.1016/j.smim.2010.04.016

Source DB:  PubMed          Journal:  Semin Immunol        ISSN: 1044-5323            Impact factor:   11.130


  82 in total

Review 1.  T-cell development made simple.

Authors:  Juan Carlos Zúñiga-Pflücker
Journal:  Nat Rev Immunol       Date:  2004-01       Impact factor: 53.106

2.  Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv mice.

Authors:  Laura A Napolitano; Cheryl A Stoddart; Mary Beth Hanley; Eric Wieder; Joseph M McCune
Journal:  J Immunol       Date:  2003-07-15       Impact factor: 5.422

3.  Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential.

Authors:  Colin H Martin; Iannis Aifantis; M Lucila Scimone; Ulrich H von Andrian; Boris Reizis; Harald von Boehmer; Fotini Gounari
Journal:  Nat Immunol       Date:  2003-08-17       Impact factor: 25.606

4.  Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages.

Authors:  Helen E Porritt; Lynn L Rumfelt; Sahba Tabrizifard; Thomas M Schmitt; Juan Carlos Zúñiga-Pflücker; Howard T Petrie
Journal:  Immunity       Date:  2004-06       Impact factor: 31.745

5.  Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968-99.

Authors:  Corinne Antoine; Susanna Müller; Andrew Cant; Marina Cavazzana-Calvo; Paul Veys; Jaak Vossen; Anders Fasth; Carsten Heilmann; Nicolas Wulffraat; Reinhard Seger; Stéphane Blanche; Wilhelm Friedrich; Mario Abinun; Graham Davies; Robert Bredius; Ansgar Schulz; Paul Landais; Alain Fischer
Journal:  Lancet       Date:  2003-02-15       Impact factor: 79.321

6.  T cell repertoire development in humans with SCID after nonablative allogeneic marrow transplantation.

Authors:  Marcella Sarzotti; Dhavalkumar D Patel; Xiaojing Li; Daniel A Ozaki; Shui Cao; Scott Langdon; Roberta E Parrott; Katherine Coyne; Rebecca H Buckley
Journal:  J Immunol       Date:  2003-03-01       Impact factor: 5.422

7.  L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor.

Authors:  S Scott Perry; Hongfang Wang; L Jeanne Pierce; Anne Marie Yang; Schickwann Tsai; Gerald J Spangrude
Journal:  Blood       Date:  2003-12-30       Impact factor: 22.113

8.  Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation.

Authors:  C Justin Van De Wiele; Julie H Marino; Bryce W Murray; Stephen S Vo; Michael E Whetsell; T Kent Teague
Journal:  J Immunol       Date:  2004-04-01       Impact factor: 5.422

9.  Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice.

Authors:  Helen E Porritt; Kristie Gordon; Howard T Petrie
Journal:  J Exp Med       Date:  2003-09-15       Impact factor: 14.307

10.  Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors.

Authors:  William E Jenkinson; Eric J Jenkinson; Graham Anderson
Journal:  J Exp Med       Date:  2003-07-14       Impact factor: 14.307

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  17 in total

1.  Identification of the earliest natural killer cell-committed progenitor in murine bone marrow.

Authors:  John W Fathman; Deepta Bhattacharya; Matthew A Inlay; Jun Seita; Holger Karsunky; Irving L Weissman
Journal:  Blood       Date:  2011-09-19       Impact factor: 22.113

Review 2.  Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.

Authors:  Ellen V Rothenberg; Jonas Ungerbäck; Ameya Champhekar
Journal:  Adv Immunol       Date:  2015-10-26       Impact factor: 3.543

3.  High levels of IL-7 cause dysregulation of thymocyte development.

Authors:  Nahed El-Kassar; Francis A Flomerfelt; Baishakhi Choudhury; Lee A Hugar; Kevin S Chua; Veena Kapoor; Philip J Lucas; Ronald E Gress
Journal:  Int Immunol       Date:  2012-08-16       Impact factor: 4.823

Review 4.  Thymic T-cell development in allogeneic stem cell transplantation.

Authors:  Werner Krenger; Bruce R Blazar; Georg A Holländer
Journal:  Blood       Date:  2011-03-22       Impact factor: 22.113

Review 5.  Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia.

Authors:  Ye Shen; Taylor J Chen; H Daniel Lacorazza
Journal:  Exp Hematol       Date:  2017-05-04       Impact factor: 3.084

Review 6.  Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell development.

Authors:  Changwan Hong; Megan A Luckey; Jung-Hyun Park
Journal:  Semin Immunol       Date:  2012-03-14       Impact factor: 11.130

7.  New insights into IL-7 signaling pathways during early and late T cell development.

Authors:  Na Niu; Xuebin Qin
Journal:  Cell Mol Immunol       Date:  2013-04-15       Impact factor: 11.530

8.  Impaired thymic expression of tissue-restricted antigens licenses the de novo generation of autoreactive CD4+ T cells in acute GVHD.

Authors:  Simone Dertschnig; Mathias M Hauri-Hohl; Madeleine Vollmer; Georg A Holländer; Werner Krenger
Journal:  Blood       Date:  2015-02-17       Impact factor: 22.113

Review 9.  Cytokines of the γ(c) family control CD4+ T cell differentiation and function.

Authors:  Hidehiro Yamane; William E Paul
Journal:  Nat Immunol       Date:  2012-10-18       Impact factor: 25.606

Review 10.  Producing proT cells to promote immunotherapies.

Authors:  Jastaranpreet Singh; Juan Carlos Zúñiga-Pflücker
Journal:  Int Immunol       Date:  2018-11-14       Impact factor: 4.823

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