Literature DB >> 20630289

Evaluation and prevention of the precipitate formed on interaction between sodium hypochlorite and chlorhexidine.

Shashikala Krishnamurthy1, Sunu Sudhakaran.   

Abstract

INTRODUCTION: The purpose of this study was (1) to evaluate maximum thickness the and chemical composition of the precipitate formed between sodium hypochlorite (NaOCl) and chlorhexidine (CHX) and (2) to evaluate effectiveness of absolute alcohol to remove residual NaOCl and thereby prevent the formation of the precipitate.
METHODS: Forty extracted single-rooted human teeth were decoronated, and the canals were instrumented. In the test group (Ts group), canals were irrigated with 17% EDTA and 2.5% NaOCl followed by 2% CHX. In the absolute alcohol (Aba), saline (Sa), and distilled water (Dw) groups, intermediate flushes of absolute alcohol, saline, and distilled water were used between the last two irrigants. Teeth were sectioned longitudinally and subjected to stereomicroscopic examination.
RESULTS: The Ts group samples showed orange-brown precipitate, concentrated more in the coronal and middle thirds, whereas the Aba group showed no evidence of precipitate. The Sal and Dw groups showed minimal precipitate in the coronal and middle thirds. The thickness of the precipitate was measured using the ProgRes computer software (Olympus, Hamburg, Germany). The chemical composition of the precipitate was confirmed by Beilstein and HCl tests, and the nuclear magnetic resonance imaging technique confirmed chlorine in the para position of the benzene ring.
CONCLUSION: The interaction between NaOCl and CHX resulted in an insoluble neutral salt as a precipitate that can be prevented using absolute alcohol and minimized using saline and distilled water as intermediate flushes. Copyright 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20630289     DOI: 10.1016/j.joen.2010.01.012

Source DB:  PubMed          Journal:  J Endod        ISSN: 0099-2399            Impact factor:   4.171


  20 in total

1.  An in vitro spectroscopic analysis to determine the chemical composition of the precipitate formed by mixing sodium hypochlorite and chlorhexidine.

Authors:  James B Nowicki; Daniel S Sem
Journal:  J Endod       Date:  2011-05-18       Impact factor: 4.171

2.  The effect of the irrigant QMix on removal of canal wall smear layer: an ex vivo study.

Authors:  Colin Eliot; John F Hatton; Gregory P Stewart; Charles F Hildebolt; M Jane Gillespie; James L Gutmann
Journal:  Odontology       Date:  2013-01-19       Impact factor: 2.634

3.  Do chlorhexidine and ethanol improve bond strength and durability of adhesion of fiber posts inside the root canal?

Authors:  Kerstin Bitter; Lena Aschendorff; Konrad Neumann; Uwe Blunck; Guido Sterzenbach
Journal:  Clin Oral Investig       Date:  2013-07-20       Impact factor: 3.573

4.  The use of NaOCl in combination with CHX produces cytotoxic product.

Authors:  Luciano Tavares Angelo Cintra; Simone Watanabe; Renata Oliveira Samuel; Aguinaldo Cândido da Silva Facundo; India Olinta de Azevedo Queiroz; Eloi Dezan-Júnior; João Eduardo Gomes-Filho
Journal:  Clin Oral Investig       Date:  2013-07-28       Impact factor: 3.573

5.  Root canal irrigants.

Authors:  Deivanayagam Kandaswamy; Nagendrababu Venkateshbabu
Journal:  J Conserv Dent       Date:  2010-10

6.  Cytotoxicity of QMix™ endodontic irrigating solution on human bone marrow mesenchymal stem cells.

Authors:  Ahmad Alkahtani; Sarah M Alkahtany; Amer Mahmood; Mona A Elsafadi; Abdullah M Aldahmash; Sukumaran Anil
Journal:  BMC Oral Health       Date:  2014-03-29       Impact factor: 2.757

7.  The Effect of Root Canal Irrigation with Combination of Sodium Hypo-chlorite and Chlorhexidine Gluconate on the Sealing Ability of Obturation Materials.

Authors:  Hamed Homayouni; Nima Moradi Majd; Heidar Zohrehei; Behrad Mosavari; Mamak Adel; Reyhaneh Dajmar; Ali Homayouni
Journal:  Open Dent J       Date:  2014-10-22

Review 8.  Agonistic and Antagonistic Interactions between Chlorhexidine and Other Endodontic Agents: A Critical Review.

Authors:  Zahed Mohammadi; Luciano Giardino; Flavio Palazzi; Saeed Asgary
Journal:  Iran Endod J       Date:  2014-12-24

9.  The antibacterial activity of sodium hypochlorite and chlorhexidine against Enterococcus faecalis: A review on agar diffusion and direct contact methods.

Authors:  Norhayati Luddin; Hany Mohamed Aly Ahmed
Journal:  J Conserv Dent       Date:  2013-01

10.  Interaction between lidocaine hydrochloride (with and without adrenaline) and various irrigants: A nuclear magnetic resonance analysis.

Authors:  Nirmal Vidhya; Balasubramanian Saravana Karthikeyan; Natanasabapathy Velmurugan; Mohan Abarajithan; Sivasankaran Nithyanandan
Journal:  Dent Res J (Isfahan)       Date:  2014-05
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