Literature DB >> 20630188

Microbiology of dental plaque biofilms and their role in oral health and caries.

Philip D Marsh1.   

Abstract

Dental plaque is the biofilm found naturally on teeth. Dental plaque is also implicated in dental caries, which is associated with shifts in the microbial balance of the biofilm resulting in increased proportions of acid producing and acid tolerating bacteria, especially (but not exclusively) mutans streptococci and lactobacilli. The regular intake of fermentable dietary sugars, or impaired saliva flow, produces persistent conditions of low pH within the biofilm, which selects for these cariogenic bacteria. Clinicians should prevent this disruption to the natural microbial balance of the biofilm (relevant approaches are described) rather than merely treating its consequences by restoring cavities. Copyright 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20630188     DOI: 10.1016/j.cden.2010.03.002

Source DB:  PubMed          Journal:  Dent Clin North Am        ISSN: 0011-8532


  70 in total

1.  Function of the pyruvate oxidase-lactate oxidase cascade in interspecies competition between Streptococcus oligofermentans and Streptococcus mutans.

Authors:  Lei Liu; Huichun Tong; Xiuzhu Dong
Journal:  Appl Environ Microbiol       Date:  2012-01-27       Impact factor: 4.792

2.  Hyperglycemia and xerostomia are key determinants of tooth decay in type 1 diabetic mice.

Authors:  Chih-Ko Yeh; Stephen E Harris; Sumathy Mohan; Diane Horn; Roberto Fajardo; Yong-Hee Patricia Chun; James Jorgensen; Mary Macdougall; Sherry Abboud-Werner
Journal:  Lab Invest       Date:  2012-03-26       Impact factor: 5.662

3.  Oral microbial biofilm stimulation of epithelial cell responses.

Authors:  Rebecca Peyyala; Sreenatha S Kirakodu; Karen F Novak; Jeffrey L Ebersole
Journal:  Cytokine       Date:  2012-01-21       Impact factor: 3.861

4.  Molecule Targeting Glucosyltransferase Inhibits Streptococcus mutans Biofilm Formation and Virulence.

Authors:  Zhi Ren; Tao Cui; Jumei Zeng; Lulu Chen; Wenling Zhang; Xin Xu; Lei Cheng; Mingyun Li; Jiyao Li; Xuedong Zhou; Yuqing Li
Journal:  Antimicrob Agents Chemother       Date:  2015-10-19       Impact factor: 5.191

5.  Interfacial degradation of adhesive composite restorations mediated by oral biofilms and mechanical challenge in an extracted tooth model of secondary caries.

Authors:  Carola A Carrera; Yuping Li; Ruoquiong Chen; Conrado Aparicio; Alex Fok; Joel Rudney
Journal:  J Dent       Date:  2017-08-24       Impact factor: 4.379

6.  Clinical efficacy of a specifically targeted antimicrobial peptide mouth rinse: targeted elimination of Streptococcus mutans and prevention of demineralization.

Authors:  R Sullivan; P Santarpia; S Lavender; E Gittins; Z Liu; M H Anderson; J He; W Shi; R Eckert
Journal:  Caries Res       Date:  2011-08-19       Impact factor: 4.056

7.  Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions.

Authors:  Christina J Adler; Keith Dobney; Laura S Weyrich; John Kaidonis; Alan W Walker; Wolfgang Haak; Corey J A Bradshaw; Grant Townsend; Arkadiusz Sołtysiak; Kurt W Alt; Julian Parkhill; Alan Cooper
Journal:  Nat Genet       Date:  2013-02-17       Impact factor: 38.330

8.  The oral metagenome in health and disease.

Authors:  Pedro Belda-Ferre; Luis David Alcaraz; Raúl Cabrera-Rubio; Héctor Romero; Aurea Simón-Soro; Miguel Pignatelli; Alex Mira
Journal:  ISME J       Date:  2011-06-30       Impact factor: 10.302

Review 9.  Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia.

Authors:  Fang Hua; Huixu Xie; Helen V Worthington; Susan Furness; Qi Zhang; Chunjie Li
Journal:  Cochrane Database Syst Rev       Date:  2016-10-25

Review 10.  Targeted antimicrobial treatment to re-establish a healthy microbial flora for long-term protection.

Authors:  R Eckert; R Sullivan; W Shi
Journal:  Adv Dent Res       Date:  2012-09
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