| Literature DB >> 20627800 |
Fabrizio Mattei1, Giovanna Schiavoni, David F Tough.
Abstract
Although initially identified and best characterized for their role in innate antiviral defence, type I interferons (IFN-I) are also known to have an important impact on the adaptive immune response. In part, this is linked to another long-recognised property of IFN-I, namely their ability to modify cellular proliferation and survival. Here, we review the influence of IFN-I on immune cell homeostasis, focusing on their effects on T cells and antigen-presenting cells.Mesh：
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Year: 2010 PMID： 20627800 DOI： 10.1016/j.cytogfr.2010.05.002
Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN： 1359-6101 Impact factor: 7.638