Literature DB >> 20627611

Comprehensive assessment of frailty for elderly high-risk patients undergoing cardiac surgery.

Simon Sündermann1, Anika Dademasch, Julian Praetorius, Jörg Kempfert, Todd Dewey, Volkmar Falk, Friedrich-Wilhelm Mohr, Thomas Walther.   

Abstract

OBJECTIVE: Cardiosurgical operative risk can be assessed using the logistic European system for cardiac operative risk evaluation (EuroSCORE) and the Society of Thoracic Surgeons (STS) score. Factors other than medical diagnoses and laboratory values such as the 'biological age' are not included in these scores. The aim of the study was to evaluate an additional assessment of frailty in routine cardiac surgical practice.
METHODS: 'The comprehensive assessment of frailty' test was applied to 400 patients≥74 years who were admitted to our centre between September 2008 and January 2010. For comparison, the STS score and the EuroSCORE were calculated. The primary end point was the correlation of Frailty score to 30-day mortality. A total of 206 female and 194 male patients were included.
RESULTS: Median Frailty score was 11 [7,15]. Median of logistic EuroSCORE was 8.5% [5.8%; 13.9%]. Median of STS score was 3.3% [2.1%; 5.1%]. There were low-to-moderate albeit significant correlations of Frailty score with STS score and EuroSCORE (p<0.05). There was also a significant correlation between Frailty score and observed 30-day mortality (p<0.05). Patients received isolated coronary artery bypass grafting (CABG) (n=90), isolated valve surgery (n=128), trans-catheter valve implantation (n=59) or combined procedures (n=123).
CONCLUSIONS: The comprehensive assessment of frailty is an additional tool to evaluate elderly patients adequately before cardiac surgical interventions. The Frailty score combines characteristics of the Fried criteria [1], of patient phenotype, of his physical performance and laboratory results. Further analysis on a larger patient population is warranted. A combination of the new Frailty score and the traditional scoring systems may facilitate a more accurate risk scoring in elderly high-risk patients scheduled for conventional cardiac surgery or trans-catheter aortic valve replacement. Copyright Â
© 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 20627611     DOI: 10.1016/j.ejcts.2010.04.013

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  88 in total

1.  Frailty Phenotypes, Disability, and Outcomes in Adult Candidates for Lung Transplantation.

Authors:  Jonathan P Singer; Joshua M Diamond; Cynthia J Gries; Jamiela McDonnough; Paul D Blanc; Rupal Shah; Monica Y Dean; Beverly Hersh; Paul J Wolters; Sofya Tokman; Selim M Arcasoy; Kristy Ramphal; John R Greenland; Nancy Smith; Pricilla Heffernan; Lori Shah; Pavan Shrestha; Jeffrey A Golden; Nancy P Blumenthal; Debbie Huang; Joshua Sonett; Steven Hays; Michelle Oyster; Patricia P Katz; Hilary Robbins; Melanie Brown; Lorriana E Leard; Jasleen Kukreja; Matthew Bacchetta; Errol Bush; Frank D'Ovidio; Melanie Rushefski; Kashif Raza; Jason D Christie; David J Lederer
Journal:  Am J Respir Crit Care Med       Date:  2015-12-01       Impact factor: 21.405

2.  The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients.

Authors:  Hao Cheng; Zhongmin Li; Nilas Young; Douglas Boyd; Zane Atkins; Fuhai Ji; Hong Liu
Journal:  J Cardiothorac Vasc Anesth       Date:  2016-03-03       Impact factor: 2.628

3.  The learning curve associated with transapical aortic valve implantation.

Authors:  Jörg Kempfert; Ardawan Rastan; David Holzhey; Axel Linke; Gerhard Schuler; Friedrich Wilhelm Mohr; Thomas Walther
Journal:  Ann Cardiothorac Surg       Date:  2012-07

4.  Association between frailty and short- and long-term outcomes among critically ill patients: a multicentre prospective cohort study.

Authors:  Sean M Bagshaw; H Thomas Stelfox; Robert C McDermid; Darryl B Rolfson; Ross T Tsuyuki; Nadia Baig; Barbara Artiuch; Quazi Ibrahim; Daniel E Stollery; Ella Rokosh; Sumit R Majumdar
Journal:  CMAJ       Date:  2013-11-25       Impact factor: 8.262

5.  Predictors of poor outcomes after transcatheter aortic valve replacement: results from the PARTNER (Placement of Aortic Transcatheter Valve) trial.

Authors:  Suzanne V Arnold; Matthew R Reynolds; Yang Lei; Elizabeth A Magnuson; Ajay J Kirtane; Susheel K Kodali; Alan Zajarias; Vinod H Thourani; Philip Green; Josep Rodés-Cabau; Nirat Beohar; Michael J Mack; Martin B Leon; David J Cohen
Journal:  Circulation       Date:  2014-05-23       Impact factor: 29.690

Review 6.  Futility, benefit, and transcatheter aortic valve replacement.

Authors:  Brian R Lindman; Karen P Alexander; Patrick T O'Gara; Jonathan Afilalo
Journal:  JACC Cardiovasc Interv       Date:  2014-06-18       Impact factor: 11.195

Review 7.  Frailty in cardiothoracic surgery: systematic review of the literature.

Authors:  Hiroshi Furukawa; Kazuo Tanemoto
Journal:  Gen Thorac Cardiovasc Surg       Date:  2015-04-28

8.  Longitudinal functional recovery after geriatric cardiac surgery.

Authors:  Lillian Min; Lauren Mazzurco; Tanya R Gure; Christine T Cigolle; Pearl Lee; Cathie Bloem; Chiao-Li Chan; Matthew A Romano; Brahmajee K Nallamothu; Kenneth M Langa; Richard L Prager; Preeti N Malani
Journal:  J Surg Res       Date:  2014-10-31       Impact factor: 2.192

9.  The impact of perceived frailty on surgeons' estimates of surgical risk.

Authors:  Mark K Ferguson; Jeanne Farnan; Josh A Hemmerich; Kris Slawinski; Julissa Acevedo; Stephen Small
Journal:  Ann Thorac Surg       Date:  2014-06-02       Impact factor: 4.330

10.  Exploring predictors of complication in older surgical patients: a deficit accumulation index and the Braden Scale.

Authors:  Rachel-Rose Cohen; Sandhya A Lagoo-Deenadayalan; Mitchell T Heflin; Richard Sloane; Irvin Eisen; Julie M Thacker; Heather E Whitson
Journal:  J Am Geriatr Soc       Date:  2012-08-20       Impact factor: 5.562

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