| Literature DB >> 20627531 |
R A Dyer1, D van Dyk, A Dresner.
Abstract
The administration of oxytocic drugs during caesarean section is an important intervention to prevent uterine atony or treat established postpartum haemorrhage. Considerable past and current research has shown that these agents have a narrow therapeutic range. A detailed knowledge by anaesthetists of optimal doses and side effects is therefore required. Oxytocin remains the first line agent. In view of receptor desensitisation, second line agents may be required, namely ergot alkaloids and prostaglandins. This review examines the adverse haemodynamic and side effects, and methods for their limitation. An approach to dosing and choices of agent for the limitation of postpartum haemorrhage is suggested. 2010 Elsevier Ltd. All rights reserved.Entities:
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Year: 2010 PMID： 20627531 DOI： 10.1016/j.ijoa.2010.04.011
Source DB: PubMed Journal: Int J Obstet Anesth ISSN： 0959-289X Impact factor: 2.603