Literature DB >> 20625294

Recent progress in facial paralysis: advances and obstacles.

Maya G Sardesai1, Kriss Moe.   

Abstract

PURPOSE OF REVIEW: Facial paralysis is a devastating and debilitating condition for which a range of management options exists; all of them continue to have limitations. We review the recent scientific literature and highlight key developments and opportunities for further exploration with the goal that this may help direct clinical practice and research endeavor. RECENT
FINDINGS: We reviewed recent findings in the evaluation of facial paralysis, pharmacological management, nerve injury prevention and treatment. This includes review of novel techniques using photography and videography. Review of surgical and adjunctive techniques identifies several refinements of existing techniques, some novel techniques, and the value of adjunctive materials and therapies.
SUMMARY: Management of facial paralysis remains an area of active investigation and innovation. The challenge to researchers and care providers will be to continue to explore and refine management strategies while maintaining rigorous and standardized means of evaluation and follow-up, such that outcomes may be determined and reported accurately and in a way that they can be transferred to other clinical practices. Further study of the role of growth factors and stem cells in facial nerve regeneration is critical, and is the most likely means of surmounting the remaining barriers to successful outcomes in alleviating the ravages of this devastating malady.

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Year:  2010        PMID: 20625294     DOI: 10.1097/MOO.0b013e32833bb16f

Source DB:  PubMed          Journal:  Curr Opin Otolaryngol Head Neck Surg        ISSN: 1068-9508            Impact factor:   2.064


  2 in total

1.  Grading Facial Nerve Function Following Combined Static and Mimetic Surgical Techniques.

Authors:  John P Leonetti; Sam J Marzo; Douglas A Anderson; Joshua M Sappington
Journal:  J Neurol Surg B Skull Base       Date:  2015-05-22

2.  Restoration of orbicularis oculi muscle function in rabbits with peripheral facial paralysis via an implantable artificial facial nerve system.

Authors:  Yajing Sun; Cheng Jin; Keyong Li; Qunfeng Zhang; Liang Geng; Xundao Liu; Yi Zhang
Journal:  Exp Ther Med       Date:  2017-09-29       Impact factor: 2.447

  2 in total

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