| Literature DB >> 20624686 |
Agnieszka Parys-Proszek1, Tomasz Kupiec, Paulina Wolańska-Nowak, Wojciech Branicki.
Abstract
Fifteen autosomal STR loci included in AmpFlSTR NGM kit were analyzed in 154 unrelated individuals from Poland. This multiplex kit enables simultaneous amplification of 10 standard STR loci included in AmpFlSTR SGM Plus kit (D3S1358, vWA, D16S539, D2S1338, D8S1179, D19S433, TH01, FGA, D21S11 and D18S51) and five new mini- and midi-STR loci (D10S1248, D22S1045, D2S441, D1S1656 and D12S391). Population study was conducted to evaluate usefulness of the loci (especially the five new microsatellite systems) in forensic genetic identification examinations. All 15 markers were found to be in Hardy-Weinberg equilibrium. The combined probability of match for the 15 studied STR loci was 3.998 x 10(-19). The same parameter calculated for five new microsatellite loci equaled 8.83 x 10(-7). Discrimination power was particularly high in case of D1S1656 (0.975) and D12S391 (0.972) STR loci. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.Entities:
Mesh:
Year: 2010 PMID: 20624686 DOI: 10.1016/j.legalmed.2010.05.002
Source DB: PubMed Journal: Leg Med (Tokyo) ISSN: 1344-6223 Impact factor: 1.376