Literature DB >> 2062419

Epidemiological investigation of the association between infectious mononucleosis and multiple sclerosis.

C Lindberg1, O Andersen, A Vahlne, M Dalton, B Runmarker.   

Abstract

By matching a cohort of 494 infectious mononucleosis (IM) cases with a multiple sclerosis (MS) register, 3 MS cases were retrieved. The interval between IM and MS was 12 years. This corresponds to a relative risk of 3.7 for MS to occur subsequent to IM (p = 0.05). This relationship between a manifestation of a relatively late Epstein-Barr virus infection and MS may indicate that a microbiologically shielded environment is important in the pathogenesis of MS.

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Year:  1991        PMID： 2062419     DOI： 10.1159/000110248

Source DB:  PubMed          Journal:  Neuroepidemiology        ISSN： 0251-5350            Impact factor:   3.282


  21 in total

1.  Acyclovir treatment of relapsing-remitting multiple sclerosis. A randomized, placebo-controlled, double-blind study.

Authors:  J Lycke; B Svennerholm; E Hjelmquist; L Frisén; G Badr; M Andersson; A Vahlne; O Andersen
Journal:  J Neurol       Date:  1996-03       Impact factor: 4.849

2.  The risk for multiple sclerosis in female nurse anaesthetists: a register based study.

Authors:  A-M Landtblom; M Tondel; P Hjalmarsson; U Flodin; O Axelson
Journal:  Occup Environ Med       Date:  2006-06       Impact factor: 4.402

Review 3.  Epstein-barr virus: environmental trigger of multiple sclerosis?

Authors:  Jan D Lünemann; Thomas Kamradt; Roland Martin; Christian Münz
Journal:  J Virol       Date:  2007-04-25       Impact factor: 5.103

4.  Multiple sclerosis and Epstein-Barr virus.

Authors:  Ruth Ann Marrie; Christina Wolfson
Journal:  Can J Infect Dis       Date:  2002-03

5.  Relation between Epstein-Barr virus and multiple sclerosis: analytic study of scientific production.

Authors:  O Santiago; J Gutierrez; A Sorlozano; J de Dios Luna; E Villegas; O Fernandez
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2010-04-29       Impact factor: 3.267

6.  Delayed infection, family size and malignant lymphomas.

Authors:  P Vineis; L Miligi; P Crosignani; A Fontana; G Masala; O Nanni; V Ramazzotti; S Rodella; E Stagnaro; R Tumino; C Viganò; C Vindigni; A S Costantini
Journal:  J Epidemiol Community Health       Date:  2000-12       Impact factor: 3.710

7.  An updated meta-analysis of risk of multiple sclerosis following infectious mononucleosis.

Authors:  Adam E Handel; Alexander J Williamson; Giulio Disanto; Lahiru Handunnetthi; Gavin Giovannoni; Sreeram V Ramagopalan
Journal:  PLoS One       Date:  2010-09-01       Impact factor: 3.240

Review 8.  Epstein-Barr virus and multiple sclerosis.

Authors:  Jan D Lünemann; Christian Münz
Journal:  Curr Neurol Neurosci Rep       Date:  2007-05       Impact factor: 5.081

9.  Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain.

Authors:  Simon N Willis; Christine Stadelmann; Scott J Rodig; Tyler Caron; Stefan Gattenloehner; Scott S Mallozzi; Jill E Roughan; Stefany E Almendinger; Megan M Blewett; Wolfgang Brück; David A Hafler; Kevin C O'Connor
Journal:  Brain       Date:  2009-12       Impact factor: 13.501

10.  Multiple sclerosis after infectious mononucleosis: record linkage study.

Authors:  Michael J Goldacre; Clare J Wotton; Valerie Seagroatt; David Yeates
Journal:  J Epidemiol Community Health       Date:  2004-12       Impact factor: 3.710
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