Literature DB >> 20622433

Inhibitory effects of bakuchiol, bavachin, and isobavachalcone isolated from Piper longum on melanin production in B16 mouse melanoma cells.

Osamu Ohno1, Taeko Watabe, Kazuhiko Nakamura, Masaru Kawagoshi, Nobuo Uotsu, Tomohiro Chiba, Masayoshi Yamada, Kohji Yamaguchi, Kaoru Yamada, Kenji Miyamoto, Daisuke Uemura.   

Abstract

An EtOH extract of fruits of Piper longum was found to exhibit a potent inhibitory effect against alpha-melanocyte-stimulating hormone (alpha-MSH)-induced melanin production in B16 mouse melanoma cells. Bioassay-directed fractionation led to the isolation of prenylated phenolic compounds bakuchiol, bavachin, and isobavachalcone. These compounds and the crude extract of the fruits of P. longum may have suppressive effects against pigmentation by melanin in the skin.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20622433     DOI： 10.1271/bbb.100221

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  8 in total

1.  Effects of bavachin and its regulation of melanin synthesis in A375 cells.

Authors:  Jing-Hua Wang; Yuan-Yuan Pei; Hong-Dan Xu; Li-Jing Li; Ye-Qiu Wang; Guo-Liang Liu; Yan Qu; Ning Zhang
Journal:  Biomed Rep       Date:  2016-05-20

2.  Psoralea glandulosa as a potential source of anticancer agents for melanoma treatment.

Authors:  Alejandro Madrid; Venera Cardile; César González; Ivan Montenegro; Joan Villena; Silvia Caggia; Adriana Graziano; Alessandra Russo
Journal:  Int J Mol Sci       Date:  2015-04-09       Impact factor: 5.923

3.  Bakuchiol suppresses proliferation of skin cancer cells by directly targeting Hck, Blk, and p38 MAP kinase.

Authors:  Jong-Eun Kim; Jae Hwan Kim; Younghyun Lee; Hee Yang; Yong-Seok Heo; Ann M Bode; Ki Won Lee; Zigang Dong
Journal:  Oncotarget       Date:  2016-03-22

4.  Screening the Marker Components in Psoralea corylifolia L. with the Aids of Spectrum-Effect Relationship and Component Knock-Out by UPLC-MS².

Authors:  Mengjun Shi; Yan Zhang; Miaomiao Song; Yong Sun; Changqin Li; Wenyi Kang
Journal:  Int J Mol Sci       Date:  2018-11-02       Impact factor: 5.923

5.  Effect of Grass Carp Scale Collagen Peptide FTGML on cAMP-PI3K/Akt and MAPK Signaling Pathways in B16F10 Melanoma Cells and Correlation between Anti-Melanin and Antioxidant Properties.

Authors:  Zizi Hu; Xiaomei Sha; Lu Zhang; Sheng Huang; Zongcai Tu
Journal:  Foods       Date:  2022-01-29

Review 6.  Bakuchiol - a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches.

Authors:  T P Adarsh Krishna; Baldev Edachery; Sunil Athalathil
Journal:  RSC Adv       Date:  2022-03-21       Impact factor: 3.361

7.  Photoprotective and antioxidant effects of Rhubarb: inhibitory action on tyrosinase and tyrosine kinase activities and TNF-α, IL-1α and α-MSH production in human melanocytes.

Authors:  Jéssica P S Silveira; Leonardo N Seito; Samara Eberlin; Gustavo C Dieamant; Cecília Nogueira; Maria C V Pereda; Luiz C Di Stasi
Journal:  BMC Complement Altern Med       Date:  2013-02-27       Impact factor: 3.659

8.  Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy.

Authors:  Qi Wu; Ai-Ling Tian; Sylvère Durand; Fanny Aprahamian; Nitharsshini Nirmalathasan; Wei Xie; Peng Liu; Liwei Zhao; Shuai Zhang; Hui Pan; Didac Carmona-Gutierrez; Frank Madeo; Yi Tu; Oliver Kepp; Guido Kroemer
Journal:  Cell Death Dis       Date:  2020-11-26       Impact factor: 8.469
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.