Three-dimensional MR microscopy with large arrays.

MR microscopy of fixed specimens is described using large (256(3] arrays. Images are acquired at 7.0 T with voxels as small as 70 x 70 x 70 microns (3.4 x 10(-4) mm3), more than 25,000 times smaller than routine clinical body imaging. Separation of the acquisition, reconstruction, archival, and analysis onto networked workstations provides flexibility and efficiency in handling the large data sets. The isotropic data can be interactively displayed through any plane without loss of in-plane resolution. The potential for applications of MR microscopy in clinical pathology is addressed.