Literature DB >> 20620936

T helper cell differentiation: understanding the needs of hierarchy.

Thomas Weichhart1, Marcus D Säemann.   

Abstract

In this issue of Immunity, Lee et al. (2010) demonstrate that the mammalian Target of Rapamycin Complex 2 promotes the differentiation of T helper 1 (Th1) cells via the kinase Akt, whereas it independently fosters Th2 cell generation via another kinase, PKC-theta. Copyright 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID: 20620936     DOI: 10.1016/j.immuni.2010.06.008

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  3 in total

1.  mTORC1/AMPK responses define a core gene set for developmental cell fate switching.

Authors:  Pundrik Jaiswal; Alan R Kimmel
Journal:  BMC Biol       Date:  2019-07-18       Impact factor: 7.431

Review 2.  mTOR Signaling in the Regulation of CD4+ T Cell Subsets in Periodontal Diseases.

Authors:  Qian Jiang; Xiaobin Huang; Wenjing Yu; Ranran Huang; Xuefeng Zhao; Chider Chen
Journal:  Front Immunol       Date:  2022-02-10       Impact factor: 8.786

3.  Immunoregulatory properties of rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation.

Authors:  Camila Macedo; Hēth Turquist; Diana Metes; Angus W Thomson
Journal:  Transplant Res       Date:  2012-09-28
  3 in total

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