BACKGROUND: Living donor kidney transplants with multiple arteries are presumed to be associated with an increased risk of complications. OBJECTIVES: The aim of the study was to compare the outcomes in living donor transplantation with the specific intention of comparing long-term outcomes in which the donor kidney had 1 or more renal arteries. The study was undertaken in 2 large transplant centers. METHODS: A retrospective analysis of 201 living donor kidney transplants with multiple arteries that were performed between January 1985 and December 2004 was undertaken. We recorded patient and graft survivals, urological and vascular complications. Kaplan-Meier survival estimates were calculated, and 2-tailed Student t-test was used to compare outcomes. P < .05 was considered statistically significant. RESULTS: Graft and patient survival at 1 year were 93% and 97% and at 5 years were 87% and 92%. The most common complications were vascular (8.9%), followed by urological (6%), acute tubular necrosis (5.5%), and posttransplant hypertension (4.0%). There was significantly higher incidence of acute tubular necrosis (ATN) in multiple-artery transplants. CONCLUSION: In this large cohort of patients studied, apart from a higher incidence of ATN and vascular complications, it appears that the number of renal arteries did not have any adverse impact on the outcomes. The findings from this study suggest that live donor kidneys with multiple renal arteries can be safely utilized for renal transplantation.
BACKGROUND: Living donor kidney transplants with multiple arteries are presumed to be associated with an increased risk of complications. OBJECTIVES: The aim of the study was to compare the outcomes in living donor transplantation with the specific intention of comparing long-term outcomes in which the donor kidney had 1 or more renal arteries. The study was undertaken in 2 large transplant centers. METHODS: A retrospective analysis of 201 living donor kidney transplants with multiple arteries that were performed between January 1985 and December 2004 was undertaken. We recorded patient and graft survivals, urological and vascular complications. Kaplan-Meier survival estimates were calculated, and 2-tailed Student t-test was used to compare outcomes. P < .05 was considered statistically significant. RESULTS: Graft and patient survival at 1 year were 93% and 97% and at 5 years were 87% and 92%. The most common complications were vascular (8.9%), followed by urological (6%), acute tubular necrosis (5.5%), and posttransplant hypertension (4.0%). There was significantly higher incidence of acute tubular necrosis (ATN) in multiple-artery transplants. CONCLUSION: In this large cohort of patients studied, apart from a higher incidence of ATN and vascular complications, it appears that the number of renal arteries did not have any adverse impact on the outcomes. The findings from this study suggest that live donor kidneys with multiple renal arteries can be safely utilized for renal transplantation.
Authors: John Fitzpatrick; Jakub Chmelo; Arjun Nambiar; Oliver Fuge; Toby Page; Gourab Sen; Naeem Soomro; David Rix; Alistair Rogers; David Talbot; Rajan Veeratterapillay Journal: Urol Ann Date: 2020-07-17
Authors: F Reyna-Sepúlveda; A Ponce-Escobedo; A Guevara-Charles; M Escobedo-Villarreal; E Pérez-Rodríguez; G Muñoz-Maldonado; M Hernández-Guedea Journal: Int J Organ Transplant Med Date: 2017-05-01
Authors: Shady A Soliman; Ahmed A Shokeir; Ahmed I Kamal; Ahmed S El-Hefnawy; Ahmed M Harraz; Mohamed M Kamal; Yasser Osman; Bedair Ali El-Dein; Ahmed B Shehab El-Dein; Mohamed A Ghoneim Journal: Arab J Urol Date: 2011-09-09
Authors: Berrin Papila Kundaktepe; Ali Vedat Durgun; Ertuğrul Göksoy; Salih Pekmezci; Metin Kapan; Kaya Sarıbeyoğlu; Mehmet Velidedeoğlu; Mehmet Eliçevik Journal: Turk J Med Sci Date: 2021-06-28 Impact factor: 0.973