Literature DB >> 20619938

Synthesis and biological evaluation of (+)-labdadienedial, derivatives and precursors from (+)-sclareolide.

Miguel A González1, Juan Mancebo-Aracil, Veronica Tangarife-Castaño, Lee Agudelo-Goméz, Bibiana Zapata, Ana Mesa-Arango, Liliana Betancur-Galvis.   

Abstract

Labdadienedial and a series of C15,C16-functionalized derivatives were synthesized from commercial (+)-sclareolide and evaluated for their cytotoxic, antimycotic, and antiviral activities. Their precursors were similarly evaluated. 2010 Elsevier Masson SAS. All rights reserved.

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Year:  2010        PMID： 20619938     DOI： 10.1016/j.ejmech.2010.06.029

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  4 in total

1.  Sclareolide enhances gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer.

Authors:  Sheng Chen; Ye Wang; Wen-Long Zhang; Mao-Sheng Dong; Jian-Hua Zhang
Journal:  Mol Med Rep       Date:  2017-02-08       Impact factor: 2.952

2.  Biological activities and cytotoxicity of diterpenes from Copaifera spp. Oleoresins.

Authors:  Fabiano de S Vargas; Patrícia D O de Almeida; Elenn Suzany P Aranha; Ana Paula de A Boleti; Peter Newton; Marne C de Vasconcellos; Valdir F Veiga Junior; Emerson S Lima
Journal:  Molecules       Date:  2015-04-09       Impact factor: 4.411

Review 3.  A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives.

Authors:  Paola Borrego-Muñoz; Felipe Ospina; Diego Quiroga
Journal:  Molecules       Date:  2021-06-30       Impact factor: 4.411

4.  α-Glucosidase and Pancreatic Lipase Inhibitory Activities of Diterpenes from Indian Mango Ginger (Curcuma amada Roxb.) and Its Derivatives.

Authors:  Yuri Yoshioka; Naori Yoshimura; Shinichi Matsumura; Hiroto Wada; Maya Hoshino; Shouhei Makino; Masanori Morimoto
Journal:  Molecules       Date:  2019-11-10       Impact factor: 4.411
  4 in total

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