PURPOSE: The aim of the study was to determine if acid-base variables are associated with hospital mortality. MATERIALS AND METHODS: This prospective cohort study took place in a university-affiliated hospital intensive care unit (ICU). One hundred seventy-five patients admitted to the ICU during the period of February to May 2007 were included in the study. We recorded clinical data and acid-base variables from all patients at ICU admission. A logistic regression model was constructed using Sepsis-related Organ Failure Assessment (SOFA) score, age, and the acid-base variables. RESULTS: Individually, none of the variables appear to be good predictors of hospital mortality. However, using the multivariate stepwise logistic regression, we had a model with good discrimination containing SOFA score, age, chloride, and albumin (area under receiver operating characteristic curve, 0.80; 95% confidence interval, 0.73-0.87). CONCLUSIONS: Hypoalbuminemia and hyperchloremia were associated with mortality. This result involving chloride is something new and should be tested in future studies.
PURPOSE: The aim of the study was to determine if acid-base variables are associated with hospital mortality. MATERIALS AND METHODS: This prospective cohort study took place in a university-affiliated hospital intensive care unit (ICU). One hundred seventy-five patients admitted to the ICU during the period of February to May 2007 were included in the study. We recorded clinical data and acid-base variables from all patients at ICU admission. A logistic regression model was constructed using Sepsis-related Organ Failure Assessment (SOFA) score, age, and the acid-base variables. RESULTS: Individually, none of the variables appear to be good predictors of hospital mortality. However, using the multivariate stepwise logistic regression, we had a model with good discrimination containing SOFA score, age, chloride, and albumin (area under receiver operating characteristic curve, 0.80; 95% confidence interval, 0.73-0.87). CONCLUSIONS:Hypoalbuminemia and hyperchloremia were associated with mortality. This result involving chloride is something new and should be tested in future studies.
Authors: Ayan Sen; Christopher M Keener; Florentina E Sileanu; Emily Foldes; Gilles Clermont; Raghavan Murugan; John A Kellum Journal: Crit Care Med Date: 2017-02 Impact factor: 7.598
Authors: Javier A Neyra; Fabrizio Canepa-Escaro; Xilong Li; John Manllo; Beverley Adams-Huet; Jerry Yee; Lenar Yessayan Journal: Crit Care Med Date: 2015-09 Impact factor: 7.598
Authors: Bruno Adler Maccagnan Pinheiro Besen; André Luiz Nunes Gobatto; Lívia Maria Garcia Melro; Alexandre Toledo Maciel; Marcelo Park Journal: World J Crit Care Med Date: 2015-05-04
Authors: J Tyler Haller; Keaton Smetana; Michael J Erdman; Todd A Miano; Heidi M Riha; Alyssa Rinaldi; Nitin Goyal; G Morgan Jones Journal: Neurohospitalist Date: 2020-03-25
Authors: Erin K Stenson; Natalie Z Cvijanovich; Nick Anas; Geoffrey L Allen; Neal J Thomas; Michael T Bigham; Scott L Weiss; Julie C Fitzgerald; Paul A Checchia; Keith Meyer; Michael Quasney; Mark Hall; Rainer Gedeit; Robert J Freishtat; Jeffrey Nowak; Shekhar S Raj; Shira Gertz; Jocelyn R Grunwell; Hector R Wong Journal: Pediatr Crit Care Med Date: 2018-02 Impact factor: 3.624
Authors: Adrian F Bulfon; Hakem L Alomani; Natalie Anton; Brooke T Comrie; Bram Rochwerg; Sorina A Stef; Lehana Thabane; Thuva Vanniyasingam; Karen Choong Journal: J Pediatr Intensive Care Date: 2019-06-19