Literature DB >> 20617861

Usefulness of endoscopic ultrasonography in preoperative gastric cancer staging: diagnostic yield and therapeutic impact.

A Repiso1, R Gómez-Rodríguez, R López-Pardo, M M Lombera, M Romero, A Aranzana, S Abad, R Rodríguez-Merlo, L López, J M Carboles.   

Abstract

OBJECTIVES: To evaluate the diagnostic yield of endoscopic ultrasonography in loco-regional staging of gastric cancer in our medium and to determine the impact of this technique on later therapeutic management.
MATERIAL AND METHODS: This is a retrospective study carried out on patients histologically diagnosed with gastric adenocarcinoma who had been referred for endoscopic ultrasonographic examination. The technique results were compared with those obtained from surgical samples and/or from exploratory laparoscopy- laparotomy. We compared the initial therapeutic decision based on conventional diagnostic techniques with the final therapeutic management based on the endoscopic ultrasonography results.
RESULTS: Forty-six patients with gastric adenocarcinoma were included in the study (a reference exploration was available in 36 cases). Diagnostic precision was 70% in stage T, while in stages T1, T2, T3 y T4 was 100, 38, 82, and 100%, respectively. The sensitivity and specificity to differentiate T1-2 from T3-4 was 94 and 85%, respectively. We could not identify factors associated with obtaining a correct diagnosis in staging T. Diagnostic precision was 72% for stage N (N0: 58%; Nx 88%). The presence of free perigastric fluid was identified in 7 cases; the presence of peritoneal carcinomatosis was later confirmed in 5 of these. The result of endoscopic ultrasonography led to a modification in the subsequent therapeutic management in 13 patients (28%).
CONCLUSIONS: Endoscopic ultrasonography is a useful technique for loco-regional staging of gastric adenocarcinoma, which may have important implications in the therapeutic management of these patients.

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Year:  2010        PMID: 20617861     DOI: 10.4321/s1130-01082010000700003

Source DB:  PubMed          Journal:  Rev Esp Enferm Dig        ISSN: 1130-0108            Impact factor:   2.086


  5 in total

Review 1.  Is endoscopic ultrasonography still the modality of choice in preoperative staging of gastric cancer?

Authors:  Sung Wook Hwang; Dong Ho Lee
Journal:  World J Gastroenterol       Date:  2014-10-14       Impact factor: 5.742

Review 2.  Diagnostic accuracy of endoscopic ultrasonography (EUS) for the preoperative locoregional staging of primary gastric cancer.

Authors:  Simone Mocellin; Sandro Pasquali
Journal:  Cochrane Database Syst Rev       Date:  2015-02-06

3.  Efficacy of endoscopic ultrasonography for prediction of tumor depth in gastric cancer.

Authors:  Ji Min Park; Chang Wook Ahn; Xian Yi; Hoon Hur; Kee Myung Lee; Yong Kwan Cho; Sang-Uk Han
Journal:  J Gastric Cancer       Date:  2011-06-30       Impact factor: 3.720

Review 4.  Peritoneal carcinomatosis: limits of diagnosis and the case for liquid biopsy.

Authors:  James R W McMullen; Matthew Selleck; Nathan R Wall; Maheswari Senthil
Journal:  Oncotarget       Date:  2017-06-27

5.  A Meta-Analysis And Systematic Review Of Accuracy Of Endoscopic Ultrasound For N Staging Of Gastric Cancers.

Authors:  Jiafei Chen; Chaoyang Zhou; Min He; Zhiming Zhen; Jie Wang; Xiaofei Hu
Journal:  Cancer Manag Res       Date:  2019-09-27       Impact factor: 3.989

  5 in total

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