Literature DB >> 20615519

Cytotoxic triterpenoids from Ganoderma lucidum.

Chun-Ru Cheng1, Qing-Xi Yue, Zhi-Yuan Wu, Xiao-Yi Song, Si-Jia Tao, Xiao-Hui Wu, Ping-Ping Xu, Xuan Liu, Shu-Hong Guan, De-An Guo.   

Abstract

A systematic study of the metabolites in Ganoderma lucidum led to isolation of 43 triterpenoids, six of them (1-6) are hitherto unknown. The structures of the latter were elucidated on the basis of spectroscopic studies and comparison with the known related compounds. All of the compounds were assayed for their inhibitory activities against human HeLa cervical cancer cell lines. Some compounds exhibit significant cytotoxicity, and their structure-activity relationships are discussed. (c) 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20615519     DOI: 10.1016/j.phytochem.2010.06.005

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  10 in total

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Review 7.  Effect of medicinal mushrooms on blood cells under conditions of diabetes mellitus.

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8.  The Effect of Mushroom Extracts on Human Platelet and Blood Coagulation: In vitro Screening of Eight Edible Species.

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Journal:  Nutrients       Date:  2019-12-12       Impact factor: 5.717

9.  The Antitumor Effects of Triterpenoid Saponins from the Anemone flaccida and the Underlying Mechanism.

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10.  Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells.

Authors:  Lijun Qu; Sumei Li; Yumin Zhuo; Jianfan Chen; Xiaoping Qin; Guoqing Guo
Journal:  Oncol Lett       Date:  2017-10-09       Impact factor: 2.967

  10 in total

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