Literature DB >> 20610315

Tocilizumab: therapy and safety management.

Thao Pham1, Pascal Claudepierre, Arnaud Constantin, Michel de Bandt, Bruno Fautrel, Laure Gossec, Jacques-Eric Gottenberg, Philippe Goupille, Séverine Guillaume, Eric Hachulla, Charles Masson, Jacques Morel, Xavier Puéchal, Alain Saraux, Thierry Schaeverbeke, Daniel Wendling, Eric Bruckert, Stanislas Pol, Xavier Mariette, Jean Sibilia.   

Abstract

OBJECTIVES: To develop fact sheets about tocilizumab, in order to assist physicians in the management of patients with inflammatory joint disease.
METHODS: 1. selection by a committee of rheumatology experts of the main topics of interest for which fact sheets were desirable; 2. identification and review of publications relevant to each topic; 3. development of fact sheets based on three levels of evidence: evidence-based medicine, official recommendations, and expert opinion. The 20 experts were rheumatologists and invited specialists in other fields, and they had extensive experience with the management of RA. They were members of the CRI (Club Rhumatismes et Inflammation), a section of the Société Francaise de Rhumatologie. Each fact sheet was revised by several. experts and the overall process was coordinated by three experts.
RESULTS: Several topics of major interest were selected: contraindications of tocilizumab; the management of adverse effects and concomitant diseases that may develop during tocilizumab therapy; and the management of everyday situations such as pregnancy, surgery, and immunizations. After a review of the literature and discussions among experts, a consensus was developed about the content of the fact sheets presented here. These fact sheets focus on several points: Several topics of major interest were selected: contraindications of tocilizumab; the management of adverse effects and concomitant diseases that may develop during tocilizumab therapy; and the management of everyday situations such as pregnancy, surgery, and immunizations. After a review of the literature and discussions among experts, a consensus was developed about the content of the fact sheets presented here. These fact sheets focus on several points: 1. in RA, initiation and monitoring of tocilizumab therapy, management of patients with specific past histories, and specific clinical situations such as pregnancy; 2. diseases other than RA, such as juvenile idiopathic arthritis; 3. models of letters for informing the rheumatologist and general practitioner; 4. and patient information.
CONCLUSION: These tocilizumab fact sheets built on evidence-based medicine and expert opinion will serve as a practical tool for assisting physicians who manage patients on tocilizumab therapy. They will be available continuously at www.cri-net.com and updated at appropriate intervals. Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.

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Year:  2010        PMID: 20610315     DOI: 10.1016/S1297-319X(10)70001-4

Source DB:  PubMed          Journal:  Joint Bone Spine        ISSN: 1297-319X            Impact factor:   4.929


  11 in total

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Review 5.  Comparison of national clinical practice guidelines and recommendations on vaccination of adult patients with autoimmune rheumatic diseases.

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6.  Does tocilizumab contribute to elevation of rheumatoid factor and induction of paradoxical syaloadenitis in rheumatoid arthritis patients?

Authors:  Dušanka Martinović Kaliterna; Jure Aljinović; Dijana Perković; Daniela Marasović Krstulović; Ivanka Marinović; Tonko Vlak
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Review 7.  Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use.

Authors:  Johanna M W Hazes; Pierre G Coulie; Vincent Geenen; Séverine Vermeire; Franck Carbonnel; Edouard Louis; Pierre Masson; Filip De Keyser
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Review 8.  The Practice Guideline for Vaccinating Korean Patients with Autoimmune Inflammatory Rheumatic Disease.

Authors:  Yu Bin Seo; Su Jin Moon; Chan Hong Jeon; Joon Young Song; Yoon Kyoung Sung; Su Jin Jeong; Ki Tae Kwon; Eu Suk Kim; Jae Hoon Kim; Hyoun Ah Kim; Dong Jin Park; Sung Hoon Park; Jin Kyun Park; Joong Kyong Ahn; Ji Seon Oh; Jae Won Yun; Joo Hyun Lee; Hee Young Lee; Min Joo Choi; Won Suk Choi; Young Hwa Choi; Jung Hyun Choi; Jung Yeon Heo; Hee Jin Cheong; Shin Seok Lee
Journal:  Infect Chemother       Date:  2020-06

9.  Efficacy of a nurse-led patient education intervention in promoting safety skills of patients with inflammatory arthritis treated with biologics: a multicentre randomised clinical trial.

Authors:  Catherine Beauvais; Françoise Fayet; Alexandra Rousseau; Christelle Sordet; Sophie Pouplin; Yves Maugars; Rose Marie Poilverd; Carine Savel; Véronique Ségard; Béatrice Godon; Christian L'amour; Aleth Perdriger; Fabienne Brin; Patricia Peyrard; Fabienne Chalier; Béatrice Pallot-Prades; Sophie Tuffet; Isabelle Griffoul; Laure Gossec
Journal:  RMD Open       Date:  2022-03

Review 10.  Antirheumatic drugs and reproduction in women and men with chronic arthritis.

Authors:  Chiara Bazzani; Laura Andreoli; Michele Agosti; Cecilia Nalli; Angela Tincani
Journal:  RMD Open       Date:  2015-08-15
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