| Literature DB >> 20609458 |
Thibault Coursindel1, Audrey Restouin, Georges Dewynter, Jean Martinez, Yves Collette, Isabelle Parrot.
Abstract
Ring contraction of 2,5-diketopiperazines by TRAL-alkylation led us to the stereoselective synthesis of original pyrrolidine-2,4-diones, a novel series of promising molecules with moderate anti-proliferative activity on breast cancer cells. 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID： 20609458 DOI： 10.1016/j.bioorg.2010.05.002
Source DB: PubMed Journal: Bioorg Chem ISSN： 0045-2068 Impact factor: 5.275