Literature DB >> 20605449

Synthesis and properties of fluorescence probe for detection of peroxides in mitochondria.

Kosei Shioji1, Yu Oyama, Kentaro Okuma, Hiroyuki Nakagawa.   

Abstract

In this study, a new type of fluorescence probe, diphenylpyrenylphosphine-conjugated alkyltriphenylphosphonium iodide which was accumulated in mitochondria, has been synthesized. This probe was detected peroxide in living cell. Comparison of the reactivity toward several peroxide indicated that the probe was existed in mitochondrial membrane. Using this probe, generation of peroxide in mitochondria of living cell was successfully visualized. 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20605449     DOI： 10.1016/j.bmcl.2010.05.017

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  Mitochondrial Redox Opto-Lipidomics Reveals Mono-Oxygenated Cardiolipins as Pro-Apoptotic Death Signals.

Authors:  Gaowei Mao; Feng Qu; Claudette M St Croix; Yulia Y Tyurina; Joan Planas-Iglesias; Jianfei Jiang; Zhentai Huang; Andrew A Amoscato; Vladimir A Tyurin; Alexandr A Kapralov; Amin Cheikhi; John Maguire; Judith Klein-Seetharaman; Hülya Bayır; Valerian E Kagan
Journal:  ACS Chem Biol       Date:  2016-01-05       Impact factor: 5.100

2.  Solasonine Causes Redox Imbalance and Mitochondrial Oxidative Stress of Ferroptosis in Lung Adenocarcinoma.

Authors:  Yao-Ying Zeng; Ying-Bin Luo; Xu-Dong Ju; Bo Zhang; Ya-Jing Cui; Yan-Bin Pan; Jian-Hui Tian; Wen-Jing Teng; Jianchun Wu; Yan Li
Journal:  Front Oncol       Date:  2022-05-18       Impact factor: 5.738

3.  Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease.

Authors:  Sugako Oka; Julio Leon; Kunihiko Sakumi; Tomomi Ide; Dongchon Kang; Frank M LaFerla; Yusaku Nakabeppu
Journal:  Sci Rep       Date:  2016-11-29       Impact factor: 4.379

4.  Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis.

Authors:  Miho Akimoto; Riruke Maruyama; Yasunari Kawabata; Yoshitsugu Tajima; Keizo Takenaga
Journal:  Cell Death Dis       Date:  2018-07-23       Impact factor: 8.469
  4 in total

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