AIMS: Microwave ablation (MWA) is the most recent development in the field of local ablative therapies. The aim of this study was to evaluate the variability and reproducibility of single-probe MWA vs. radiofrequency ablation (RFA) of liver metastases smaller than 3cm in patients without underlying liver disease. METHODS: Sixteen liver metastases were treated using MWA, and matched for size and localisation with 13 metastases treated by RFA. Tumour diameters and postoperative ablation diameters were recorded (D1 transverse; D2 antero-posterior; D3 cranio-caudal; mm) on computed tomography scans. RESULTS: Median D1, D2, and D3 ablation diameters after MWA vs. RFA were 18.5 (12-64) vs. 34 (16-41)mm (p=0.003), 26 (14-60) vs. 35 (28-40)mm (p=0.046), and 20 (10-73) vs. 32 (20-45)mm (p=0.025), respectively. As compared to RFA, the variability between the lesions after MWA was significantly higher for D2 (p<0.0001) and D3 (p=0.002) but not for D1 (p=0.15). The ablation diameters were less uniform after MWA than after RFA (p<0.001). CONCLUSION: Ablation diameters after single-probe MWA of metastatic liver tumours are highly variable and suboptimal. Improvements are needed before MWA can be implemented routinely. Copyright (c) 2010 Elsevier Ltd. All rights reserved.
AIMS: Microwave ablation (MWA) is the most recent development in the field of local ablative therapies. The aim of this study was to evaluate the variability and reproducibility of single-probe MWA vs. radiofrequency ablation (RFA) of liver metastases smaller than 3cm in patients without underlying liver disease. METHODS: Sixteen liver metastases were treated using MWA, and matched for size and localisation with 13 metastases treated by RFA. Tumour diameters and postoperative ablation diameters were recorded (D1 transverse; D2 antero-posterior; D3 cranio-caudal; mm) on computed tomography scans. RESULTS: Median D1, D2, and D3 ablation diameters after MWA vs. RFA were 18.5 (12-64) vs. 34 (16-41)mm (p=0.003), 26 (14-60) vs. 35 (28-40)mm (p=0.046), and 20 (10-73) vs. 32 (20-45)mm (p=0.025), respectively. As compared to RFA, the variability between the lesions after MWA was significantly higher for D2 (p<0.0001) and D3 (p=0.002) but not for D1 (p=0.15). The ablation diameters were less uniform after MWA than after RFA (p<0.001). CONCLUSION: Ablation diameters after single-probe MWA of metastatic liver tumours are highly variable and suboptimal. Improvements are needed before MWA can be implemented routinely. Copyright (c) 2010 Elsevier Ltd. All rights reserved.
Authors: José Irving Hernández; Mario Francisco Jesús Cepeda; Francisco Valdés; Geshel David Guerrero Journal: Onco Targets Ther Date: 2015-07-06 Impact factor: 4.147
Authors: Mrudula B Glassberg; Sudip Ghosh; Jeffrey W Clymer; Rana A Qadeer; Nicole C Ferko; Behnam Sadeghirad; George Wj Wright; Joseph F Amaral Journal: Onco Targets Ther Date: 2019-08-13 Impact factor: 4.147