OBJECTIVE: To determine whether longer durations of voucher-based reinforcement therapy (VBRT) increase long-term abstinence compared to standard durations. METHODS:Cocaine-abusing or dependent methadone-maintenance patients (N = 130) were randomized to receive either Standard (12-week; n = 62) or Extended (36-week; n = 68) VBRT. Participants provided 3 urine samples weekly during VBRT, and each cocaine-negative sample produced a voucher exchangeable for goods and services. RESULTS: Extended VBRT produced longer durations of self-reported continuous abstinence during study Year 1 (M = 74 vs. 46 days; F(1,128) = 5.23, P = 0.024), but not during Year 2. However, each week of abstinence during Year 1 was associated with an increase of 9.19 days of abstinence during Year 2, regardless of study condition (t(1) = 4.92, P < 0.001). CONCLUSIONS: Longer-duration VBRT can increase abstinence during VBRT, but may not maintain it afterwards. However, longer during-treatment abstinence begets later abstinence suggesting that further research regarding this relationship is needed.
RCT Entities:
OBJECTIVE: To determine whether longer durations of voucher-based reinforcement therapy (VBRT) increase long-term abstinence compared to standard durations. METHODS:Cocaine-abusing or dependent methadone-maintenance patients (N = 130) were randomized to receive either Standard (12-week; n = 62) or Extended (36-week; n = 68) VBRT. Participants provided 3 urine samples weekly during VBRT, and each cocaine-negative sample produced a voucher exchangeable for goods and services. RESULTS: Extended VBRT produced longer durations of self-reported continuous abstinence during study Year 1 (M = 74 vs. 46 days; F(1,128) = 5.23, P = 0.024), but not during Year 2. However, each week of abstinence during Year 1 was associated with an increase of 9.19 days of abstinence during Year 2, regardless of study condition (t(1) = 4.92, P < 0.001). CONCLUSIONS: Longer-duration VBRT can increase abstinence during VBRT, but may not maintain it afterwards. However, longer during-treatment abstinence begets later abstinence suggesting that further research regarding this relationship is needed.
Authors: Maxine L Stitzer; Jessica Peirce; Nancy M Petry; Kimberly Kirby; John Roll; Joseph Krasnansky; Allan Cohen; Jack Blaine; Ryan Vandrey; Ken Kolodner; Rui Li Journal: Exp Clin Psychopharmacol Date: 2007-08 Impact factor: 3.157
Authors: Kimberly C Kirby; Carolyn M Carpenedo; Maxine L Stitzer; Karen L Dugosh; Nancy M Petry; John M Roll; Michael E Saladin; Allan J Cohen; John Hamilton; Karen Reese; Gina R Sillo; Patricia Quinn Stabile; Robert C Sterling Journal: J Subst Abuse Treat Date: 2011-11-23