Literature DB >> 20603199

Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum.

Sri Fatmawati1, Kuniyoshi Shimizu, Ryuichiro Kondo.   

Abstract

Ganoderic acid Df, a new lanostane-type triterpenoid, was isolated from the fruiting body of Ganoderma lucidum. Its structure was characterized as 7β, 11β-dihydroxy-3, 15, 23-trioxo-5α-lanosta-8-en-26-oic acid by 1D- and 2D-NMR spectra. This compound exhibited potent human aldose reductase inhibitory activity, with an IC(50) of 22.8 μM in vitro. A carboxyl group of this compound's side chain is essential for eliciting inhibitory activity because its methyl ester is much less active.
Copyright © 2010 Elsevier B.V. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20603199     DOI： 10.1016/j.fitote.2010.06.025

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  8 in total

1.  [20(22)E]-Lanostane Triterpenes from the Fungus Ganoderma australe.

Authors:  Lin Zhou; Li-Li Guo; Masahiko Isaka; Zheng-Hui Li; He-Ping Chen
Journal:  J Fungi (Basel)       Date:  2022-05-12

Review 2.  Accessing biological actions of Ganoderma secondary metabolites by in silico profiling.

Authors:  Ulrike Grienke; Teresa Kaserer; Florian Pfluger; Christina E Mair; Thierry Langer; Daniela Schuster; Judith M Rollinger
Journal:  Phytochemistry       Date:  2014-11-06       Impact factor: 4.072

Review 3.  Nutraceuticals in prevention of cataract - An evidence based approach.

Authors:  Amandeep Kaur; Vikas Gupta; Ajay Francis Christopher; Manzoor Ahmad Malik; Parveen Bansal
Journal:  Saudi J Ophthalmol       Date:  2016-12-18

4.  Molecular docking based screening of triterpenoids as potential G-quadruplex stabilizing ligands with anti-cancer activity.

Authors:  Sittichai Sillapapongwarakorn; Somchai Yanarojana; Darawan Pinthong; Amnuay Thithapandha; Jiraporn Ungwitayatorn; Porntip Supavilai
Journal:  Bioinformation       Date:  2017-09-30

5.  Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi.

Authors:  Xiao-Ling Wang; Zhong-Yang Ding; Gao-Qiang Liu; Hailong Yang; Guo-Ying Zhou
Journal:  Molecules       Date:  2016-10-20       Impact factor: 4.411

Review 6.  The beneficial effects of Ganoderma lucidum on cardiovascular and metabolic disease risk.

Authors:  Sze Wa Chan; Brian Tomlinson; Paul Chan; Christopher Wai Kei Lam
Journal:  Pharm Biol       Date:  2021-12       Impact factor: 3.503

Review 7.  Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research.

Authors:  Vuanghao Lim; Edward Schneider; Hongli Wu; Iok-Hou Pang
Journal:  Nutrients       Date:  2018-10-26       Impact factor: 5.717

Review 8.  Mushrooms of the Genus Ganoderma Used to Treat Diabetes and Insulin Resistance.

Authors:  Katarzyna Wińska; Wanda Mączka; Klaudia Gabryelska; Małgorzata Grabarczyk
Journal:  Molecules       Date:  2019-11-11       Impact factor: 4.411
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.