Literature DB >> 20603007

Metabolic networks of longevity.

Riekelt H Houtkooper1, Robert W Williams, Johan Auwerx.   

Abstract

Molecular and cellular networks implicated in aging depend on a multitude of proteins that collectively mount adaptive and contingent metabolic responses to environmental challenges. Here, we discuss the intimate links between metabolic regulation and longevity and outline new approaches for analyzing and manipulating such links to promote human health span. Copyright 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20603007      PMCID： PMC3852811          DOI： 10.1016/j.cell.2010.06.029

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  39 in total

1.  Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle.

Authors:  Carles Cantó; Lake Q Jiang; Atul S Deshmukh; Chikage Mataki; Agnes Coste; Marie Lagouge; Juleen R Zierath; Johan Auwerx
Journal:  Cell Metab       Date:  2010-03-03       Impact factor: 27.287

2.  Ppargamma2 is a key driver of longevity in the mouse.

Authors:  Carmen Argmann; Radu Dobrin; Sami Heikkinen; Aurélie Auburtin; Laurent Pouilly; Terrie-Anne Cock; Hana Koutnikova; Jun Zhu; Eric E Schadt; Johan Auwerx
Journal:  PLoS Genet       Date:  2009-12-04       Impact factor: 5.917

Review 3.  Caloric restriction, SIRT1 and longevity.

Authors:  Carles Cantó; Johan Auwerx
Journal:  Trends Endocrinol Metab       Date:  2009-08-25       Impact factor: 12.015

4.  Resveratrol is not a direct activator of SIRT1 enzyme activity.

Authors:  Dirk Beher; John Wu; Suzanne Cumine; Ki Won Kim; Shu-Chen Lu; Larissa Atangan; Minghan Wang
Journal:  Chem Biol Drug Des       Date:  2009-10-20       Impact factor: 2.817

5.  Induction of autophagy by spermidine promotes longevity.

Authors:  Tobias Eisenberg; Heide Knauer; Alexandra Schauer; Sabrina Büttner; Christoph Ruckenstuhl; Didac Carmona-Gutierrez; Julia Ring; Sabrina Schroeder; Christoph Magnes; Lucia Antonacci; Heike Fussi; Luiza Deszcz; Regina Hartl; Elisabeth Schraml; Alfredo Criollo; Evgenia Megalou; Daniela Weiskopf; Peter Laun; Gino Heeren; Michael Breitenbach; Beatrix Grubeck-Loebenstein; Eva Herker; Birthe Fahrenkrog; Kai-Uwe Fröhlich; Frank Sinner; Nektarios Tavernarakis; Nadege Minois; Guido Kroemer; Frank Madeo
Journal:  Nat Cell Biol       Date:  2009-10-04       Impact factor: 28.824

6.  4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila.

Authors:  Brian M Zid; Aric N Rogers; Subhash D Katewa; Misha A Vargas; Marysia C Kolipinski; Tony Au Lu; Seymour Benzer; Pankaj Kapahi
Journal:  Cell       Date:  2009-10-02       Impact factor: 41.582

7.  AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol.

Authors:  Jee-Hyun Um; Sung-Jun Park; Hyeog Kang; Shutong Yang; Marc Foretz; Michael W McBurney; Myung K Kim; Benoit Viollet; Jay H Chung
Journal:  Diabetes       Date:  2009-11-23       Impact factor: 9.461

8.  Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster.

Authors:  Ivana Bjedov; Janne M Toivonen; Fiona Kerr; Cathy Slack; Jake Jacobson; Andrea Foley; Linda Partridge
Journal:  Cell Metab       Date:  2010-01       Impact factor: 27.287

9.  Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila.

Authors:  Richard C Grandison; Matthew D W Piper; Linda Partridge
Journal:  Nature       Date:  2009-12-02       Impact factor: 49.962

10.  Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.

Authors:  David E Harrison; Randy Strong; Zelton Dave Sharp; James F Nelson; Clinton M Astle; Kevin Flurkey; Nancy L Nadon; J Erby Wilkinson; Krystyna Frenkel; Christy S Carter; Marco Pahor; Martin A Javors; Elizabeth Fernandez; Richard A Miller
Journal:  Nature       Date:  2009-07-08       Impact factor: 49.962
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  87 in total

1.  Genetic perturbation of key central metabolic genes extends lifespan in Drosophila and affects response to dietary restriction.

Authors:  Matthew E Talbert; Brittany Barnett; Robert Hoff; Maria Amella; Kate Kuczynski; Erik Lavington; Spencer Koury; Evgeny Brud; Walter F Eanes
Journal:  Proc Biol Sci       Date:  2015-09-22       Impact factor: 5.349

Review 2.  Cellular Metabolism and Aging.

Authors:  Andre Catic
Journal:  Prog Mol Biol Transl Sci       Date:  2018-02-01       Impact factor: 3.622

Review 3.  Reconsidering the Role of Mitochondria in Aging.

Authors:  Marta Gonzalez-Freire; Rafael de Cabo; Michel Bernier; Steven J Sollott; Elisa Fabbri; Placido Navas; Luigi Ferrucci
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2015-05-20       Impact factor: 6.053

Review 4.  Hypothalamic microinflammation: a common basis of metabolic syndrome and aging.

Authors:  Yizhe Tang; Sudarshana Purkayastha; Dongsheng Cai
Journal:  Trends Neurosci       Date:  2014-11-14       Impact factor: 13.837

5.  Antagonistic functions of LMNA isoforms in energy expenditure and lifespan.

Authors:  Isabel C Lopez-Mejia; Marion de Toledo; Carine Chavey; Laure Lapasset; Patricia Cavelier; Celia Lopez-Herrera; Karim Chebli; Philippe Fort; Guillaume Beranger; Lluis Fajas; Ez Z Amri; Francois Casas; Jamal Tazi
Journal:  EMBO Rep       Date:  2014-03-17       Impact factor: 8.807

Review 6.  Ketogenic diets, mitochondria, and neurological diseases.

Authors:  Lindsey B Gano; Manisha Patel; Jong M Rho
Journal:  J Lipid Res       Date:  2014-05-20       Impact factor: 5.922

Review 7.  Understanding the physiology of the ageing individual: computational modelling of changes in metabolism and endurance.

Authors:  Johannes H G M van Beek; Thomas B L Kirkwood; James B Bassingthwaighte
Journal:  Interface Focus       Date:  2016-04-06       Impact factor: 3.906

Review 8.  The PARP family: insights into functional aspects of poly (ADP-ribose) polymerase-1 in cell growth and survival.

Authors:  T Jubin; A Kadam; M Jariwala; S Bhatt; S Sutariya; A R Gani; S Gautam; R Begum
Journal:  Cell Prolif       Date:  2016-06-22       Impact factor: 6.831

9.  Sirtuin Deacetylation Mechanism and Catalytic Role of the Dynamic Cofactor Binding Loop.

Authors:  Yawei Shi; Yanzi Zhou; Shenglong Wang; Yingkai Zhang
Journal:  J Phys Chem Lett       Date:  2013-02-07       Impact factor: 6.475

10.  Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies.

Authors:  Drew Stenesen; Jae Myoung Suh; Jin Seo; Kweon Yu; Kyu-Sun Lee; Jong-Seok Kim; Kyung-Jin Min; Jonathan M Graff
Journal:  Cell Metab       Date:  2013-01-08       Impact factor: 27.287
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