Literature DB >> 20602325

Severe global inflammatory involvement of ocular segments and optic disc swelling in a 12-year-old girl with Kawasaki disease.

Erick Grouteau1, Cécile Debuisson, Karine Brochard, Soizic Paranon, Cécile Lesage Beaudon, Christine Pajot, Isabelle Claudet.   

Abstract

PURPOSE: Pediatric Kawasaki ocular involvement is dominated by bulbar conjunctival injection and mild, self-limited anterior uveitis. Posterior segment involvement is rare. METHODS/
RESULTS: Case Report. Despite early efficient treatment including aspirin and intravenous immunoglobulins, a 12-year-old girl developed a severe bilateral global inflammatory ocular involvement including punctuated keratitis, retrodescemetic precipitates, anterior uveitis, vitritis, and bilateral optic disc swelling with papillitis. DISCUSSION: This is the first description of severe bilateral global inflammatory involvement of the eyes in Kawasaki disease (KD). Usually subclinical and self-limited, eye involvement in KD can lead to severe visual impairment.
CONCLUSIONS: Inflammation of both anterior and posterior segments does not seem to respond to KD-specific treatment and could justify a specific ophthalmologic therapeutic approach.

Entities:  

Mesh:

Year:  2011        PMID: 20602325     DOI: 10.5301/ejo.2010.606

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  6 in total

1.  Macular oedema in Kawasaki syndrome.

Authors:  Justus G Garweg; Claudia Suter; Christine Aebi-Ochsner; Reto Villiger
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-01-06       Impact factor: 3.117

2.  Retinal Vasculitis in Kawasaki Disease.

Authors:  Sikha Agarwal; Samyak Mulkutkar; Deepti Suri; Surjit Singh; Amod Gupta
Journal:  Indian J Pediatr       Date:  2015-05-21       Impact factor: 1.967

3.  Potential intravenous immunoglobulin-induced optic disc edema.

Authors:  Anna K Britton; Anagha Vaze; Sam Milliken; Clare L Fraser
Journal:  Am J Ophthalmol Case Rep       Date:  2022-06-16

Review 4.  Current perspectives on ophthalmic manifestations of childhood rheumatic diseases.

Authors:  Neal V Palejwala; Steven Yeh; Sheila T Angeles-Han
Journal:  Curr Rheumatol Rep       Date:  2013-07       Impact factor: 4.592

Review 5.  Clinical Manifestations and Laboratory Findings of Kawasaki Disease: Beyond the Classic Diagnostic Features.

Authors:  Wendy Lee; Chooi San Cheah; Siti Aisyah Suhaini; Abdullah Harith Azidin; Mohammad Shukri Khoo; Noor Akmal Shareela Ismail; Adli Ali
Journal:  Medicina (Kaunas)       Date:  2022-05-30       Impact factor: 2.948

6.  Crystalline-like keratopathy after intravenous immunoglobulin therapy with incomplete kawasaki disease: case report and literature review.

Authors:  Elif Erdem; Emine Kocabas; Hande Taylan Sekeroglu; Ozlem Ozgür; Meltem Yagmur; T Reha Ersoz
Journal:  Case Rep Ophthalmol Med       Date:  2013-03-28
  6 in total

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