| Literature DB >> 20602282 |
Fan Yang1, Hong-Jun Zhang, Jian-Tao Chen, Hai-Feng Tang, Shu-Juan Piao, Wan-Sheng Chen, Hou-Wen Lin.
Abstract
Two new oxygenated sterols, 3β,24(S)-dihydroxycholesta-5,25-dien-7-one and 3β,25-dihydroxycholesta-5,23-dien-7-one, were isolated from the marine bryozoan Bugula neritina. Their chemical structures were established on the basis of spectroscopic analysis. Both compounds exhibited cytotoxicity to three human cancer cell lines (HepG2, HT-29 and NCI-H460), with IC₅₀ values between 22.58 and 53.41 µg mL⁻¹.Entities:
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Year: 2011 PMID： 20602282 DOI： 10.1080/14786410903211235
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861