CONTEXT: Pancreatitis is a very rare adverse effect of tamoxifen with only six cases of tamoxifen-associated pancreatitis reported in the English literature until now. In these cases, rechallenge with tamoxifen was not carried out. CASE REPORT: We report a case of recurrent severe acute pancreatitis in a 44-year-old female induced by tamoxifen therapy and review the literature with regards to tamoxifen-associated pancreatitis. CONCLUSION: Clinicians should be aware of the risks of developing severe acute pancreatitis when using tamoxifen therapy. If tamoxifen is suspected as the probable causative agent, rechallenge with this drug should be prohibited.
CONTEXT: Pancreatitis is a very rare adverse effect of tamoxifen with only six cases of tamoxifen-associated pancreatitis reported in the English literature until now. In these cases, rechallenge with tamoxifen was not carried out. CASE REPORT: We report a case of recurrent severe acute pancreatitis in a 44-year-old female induced by tamoxifen therapy and review the literature with regards to tamoxifen-associated pancreatitis. CONCLUSION: Clinicians should be aware of the risks of developing severe acute pancreatitis when using tamoxifen therapy. If tamoxifen is suspected as the probable causative agent, rechallenge with this drug should be prohibited.
Authors: Claudia Nitsche; Sandrina Maertin; Jonas Scheiber; Christoph A Ritter; Markus M Lerch; Julia Mayerle Journal: Curr Gastroenterol Rep Date: 2012-04
Authors: Young Ae Kim; Sol Lee; Ji Woong Jung; Yu Jin Kwon; Gyeong Bok Lee; Dong Gue Shin; Sang Su Park; Jin Yun; Yong-Seog Jang; Dong Hui Cho Journal: Chin J Cancer Res Date: 2014-06 Impact factor: 5.087