Literature DB >> 20601617

Coenzyme Q10: a therapy for hypertension and statin-induced myalgia?

Marcia Wyman1, Mandy Leonard, Thomas Morledge.   

Abstract

Some small clinical trials seem to show that coenzyme Q10 supplements can be used to lower blood pressure and to treat or prevent myalgia caused by hydroxymethylglutaryl coenzyme A reductase inhibitors (statins). However, larger trials are needed to determine if they are truly effective for these purposes. The authors examine the evidence and also discuss issues such as bioavailability, elimination, safety, and cost.

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Year:  2010        PMID: 20601617     DOI: 10.3949/ccjm.77a.09078

Source DB:  PubMed          Journal:  Cleve Clin J Med        ISSN: 0891-1150            Impact factor:   2.321


  9 in total

1.  Coenzyme q10 therapy.

Authors:  Juan Garrido-Maraver; Mario D Cordero; Manuel Oropesa-Ávila; Alejandro Fernández Vega; Mario de la Mata; Ana Delgado Pavón; Manuel de Miguel; Carmen Pérez Calero; Marina Villanueva Paz; David Cotán; José A Sánchez-Alcázar
Journal:  Mol Syndromol       Date:  2014-07

2.  Overexpression of mitochondrial antioxidant manganese superoxide dismutase (MnSOD) provides protection against AZT- or 3TC-induced endothelial dysfunction.

Authors:  Mitzi Glover; Valeria Y Hebert; Krystle Nichols; Stephen Y Xue; Taylor M Thibeaux; James A Zavecz; Tammy R Dugas
Journal:  Antiviral Res       Date:  2014-09-27       Impact factor: 5.970

Review 3.  Advancing beyond the "heart-healthy diet" for peripheral arterial disease.

Authors:  Emily V Nosova; Michael S Conte; S Marlene Grenon
Journal:  J Vasc Surg       Date:  2015-01       Impact factor: 4.268

4.  Combination of Omega 3 and Coenzyme Q10 Exerts Neuroprotective Potential Against Hypercholesterolemia-Induced Alzheimer's-Like Disease in Rats.

Authors:  Ghadha Ibrahim Fouad
Journal:  Neurochem Res       Date:  2020-03-02       Impact factor: 3.996

Review 5.  Coenzyme Q10 depletion in medical and neuropsychiatric disorders: potential repercussions and therapeutic implications.

Authors:  Gerwyn Morris; George Anderson; Michael Berk; Michael Maes
Journal:  Mol Neurobiol       Date:  2013-06-13       Impact factor: 5.590

6.  Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter niemann-pick c1-like 1 in caco-2 cells and rats.

Authors:  Mari Nekohashi; Mana Ogawa; Takuo Ogihara; Kyoko Nakazawa; Hisanori Kato; Takumi Misaka; Keiko Abe; Shoko Kobayashi
Journal:  PLoS One       Date:  2014-05-23       Impact factor: 3.240

7.  Coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study.

Authors:  Ajda Skarlovnik; Miodrag Janić; Mojca Lunder; Martina Turk; Mišo Šabovič
Journal:  Med Sci Monit       Date:  2014-11-06

8.  Reversal of statin-induced memory dysfunction by co-enzyme Q10: a case report.

Authors:  Basil N Okeahialam
Journal:  Vasc Health Risk Manag       Date:  2015-11-06

9.  Coenzyme Q10 supplementation improves metabolic parameters, liver function and mitochondrial respiration in rats with high doses of atorvastatin and a cholesterol-rich diet.

Authors:  Ma Antonia Jiménez-Santos; Isela E Juárez-Rojop; Carlos A Tovilla-Zárate; María Teresa Espinosa-García; Marco A Juárez-Oropeza; Teresa Ramón-Frías; Deysi Y Bermúdez-Ocaña; Juan C Díaz-Zagoya
Journal:  Lipids Health Dis       Date:  2014-01-25       Impact factor: 3.876

  9 in total

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