| Literature DB >> 20599984 |
Rongjun Wang1, Xiaosan Zhang, Huili Zhu, Longxian Zhang, Yaoyu Feng, Fuchun Jian, Changshen Ning, Meng Qi, Yang Zhou, Kanda Fu, Yaqiang Wang, Yanru Sun, Qiang Wang, Lihua Xiao.
Abstract
Cryptosporidium and Giardia infections are common causes of diarrhea worldwide. To better understand the transmission of human cryptosporidiosis and giardiasis in Henan, China, 10 Cryptosporidium-positive specimens and 18 Giardia-positive specimens were characterized at the species/genotype and subtype levels. Cryptosporidium specimens were analyzed by DNA sequencing of the small subunit rRNA and 60kDa glycoprotein genes. Among those genotyped, nine belonged to C. hominis and one C. felis, with the former belonging to three subtype families: Ia, Ib, and Id. The three Ib subtypes identified, IbA16G2, IbA19G2, and IbA20G2, were very different from the two common Ib subtypes (IbA9G3 and IbA10G2) found in other areas of the world. The distribution of Giardia duodenalis genotypes and subtypes was assessed by sequence analysis of the triosephosphate isomerase (tpi) gene. The assemblages A (eight belonging to A-I and four A-II) and B (belonging to six new subtypes) were found in 12 and six specimens, respectively. More systematic studies are needed to understand the transmission of Cryptosporidium and G. duodenalis in humans in China. Published by Elsevier Inc.Entities:
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Year: 2010 PMID： 20599984 DOI： 10.1016/j.exppara.2010.06.034
Source DB: PubMed Journal: Exp Parasitol ISSN： 0014-4894 Impact factor: 2.011