| Literature DB >> 20597465 |
Meikun Fan, Matthew Thompson, Maria Luiza Andrade, Alexandre G Brolo.
Abstract
A cost-effective fabrication method for the preparation of localized surface plasmon resonance (LSPR) biosensors supported on plastics is described. The silver-nanoparticles-on-plastic sensor (SNOPS) was fabricated by chemically modifying the surface of a common plastic, polyethylene terephthalate (PET) to allow the efficient immobilization of Ag NPs. The LSPR of the SNOPS strip showed good sample-to-sample reproducibility. The analytical performance of the sensor strips for monitoring both thiol and protein adsorption, including bioaffinity, was examined. The limit of quantification to the adsorption of 11-mercaptoundecanoic acid was 500 nM and for the detection of streptavidin was approximately 9.5 nM. SNOPS can then be used as a cheap, versatile, and yet sensitive LSPR biosensor.Entities:
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Year: 2010 PMID： 20597465 DOI： 10.1021/ac101495m
Source DB: PubMed Journal: Anal Chem ISSN： 0003-2700 Impact factor: 6.986