Literature DB >> 20596961

microRNA-181b targets MLK2 in HL-60 cells.

Hong Chen1, Qun Chen2, Ming Fang3, Yan Mi4.   

Abstract

microRNAs (miRNAs) play critical roles in many different cellular processes, including metabolism, apoptosis, differentiation and development. We showed miR-181b to be highly expressed in acute myeloid leukemia (AML). Furthermore, miR-181b contributed to proliferation of AML cells by targeting MLK2. Our results demonstrated that miR-181b plays an important role in the biology of AML and may be useful in developing therapies targeting miRNAs.

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Year:  2010        PMID： 20596961     DOI： 10.1007/s11427-010-0002-y

Source DB:  PubMed          Journal:  Sci China Life Sci        ISSN： 1674-7305            Impact factor:   6.038


  9 in total

1.  Inducible overexpression of zebrafish microRNA-722 suppresses chemotaxis of human neutrophil like cells.

Authors:  Alan Y Hsu; Sheng Liu; Ramizah Syahirah; Kent A Brasseale; Jun Wan; Qing Deng
Journal:  Mol Immunol       Date:  2019-06-05       Impact factor: 4.407

2.  LncRNA nuclear-enriched abundant transcript 1 regulates hypoxia-evoked apoptosis and autophagy via mediation of microRNA-181b.

Authors:  Ying Lv; Zhaoming Liu; Jiancheng Huang; Jie Yu; Yanbo Dong; Jun Wang
Journal:  Mol Cell Biochem       Date:  2019-12-18       Impact factor: 3.396

3.  miR-181b regulates vascular endothelial aging by modulating an MAP3K3 signaling pathway.

Authors:  Haoyang Zhou; Dafeng Yang; Henry S Cheng; Michael G McCoy; Daniel Pérez-Cremades; Stefan Haemmig; Danny Wong; Lei Chen; Mark W Feinberg
Journal:  FASEB J       Date:  2022-06       Impact factor: 5.834

4.  Aberrant Expression of the miR-181b/miR-222 after Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia.

Authors:  Mahdiyar Iravani Saadi; Nargess Arandi; Ramin Yaghobi; Negar Azarpira; Bita Geramizadeh; Mani Ramzi
Journal:  Indian J Hematol Blood Transfus       Date:  2019-01-21       Impact factor: 0.900

5.  miR-181b as a key regulator of the oncogenic process and its clinical implications in cancer (Review).

Authors:  Juan Liu; Weifeng Shi; Changping Wu; Jingfang Ju; Jingting Jiang
Journal:  Biomed Rep       Date:  2013-11-07

Review 6.  The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness.

Authors:  Bin Bao; Asfar S Azmi; Shadan Ali; Aamir Ahmad; Yiwei Li; Sanjeev Banerjee; Dejuan Kong; Fazlul H Sarkar
Journal:  Biochim Biophys Acta       Date:  2012-05-10

7.  Pre-microRNA and mature microRNA in human mitochondria.

Authors:  Eric Barrey; Gaelle Saint-Auret; Blandine Bonnamy; Dominique Damas; Orane Boyer; Xavier Gidrol
Journal:  PLoS One       Date:  2011-05-26       Impact factor: 3.240

Review 8.  The role of hypoxia in the tumor microenvironment and development of cancer stem cell: a novel approach to developing treatment.

Authors:  Asieh Emami Nejad; Simin Najafgholian; Alireza Rostami; Alireza Sistani; Samaneh Shojaeifar; Mojgan Esparvarinha; Reza Nedaeinia; Shaghayegh Haghjooy Javanmard; Marjan Taherian; Mojtaba Ahmadlou; Rasoul Salehi; Bahman Sadeghi; Mostafa Manian
Journal:  Cancer Cell Int       Date:  2021-01-20       Impact factor: 5.722

9.  miR-181b-5p Promotes the Progression of Cholangiocarcinoma by Targeting PARK2 via PTEN/PI3K/AKT Signaling Pathway.

Authors:  Zhe-Long Jiang; Fu-Xing Zhang; Li-Zhi Lv; Hong-Liang Zhan; He-Jun Yang; Si-Yu Zhang; Zhao-Hui Liu; Yi Jiang; Rui-Sheng Ke
Journal:  Biochem Genet       Date:  2021-06-24       Impact factor: 1.890
  9 in total

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