Literature DB >> 20595551

A prospective outcomes study of meniscal allograft transplantation.

Robert F LaPrade1, Nicholas J Wills, Stanislav I Spiridonov, Scott Perkinson.   

Abstract

BACKGROUND: Symptomatic early-onset chondromalacia often develops after a meniscectomy in the affected knee compartment. The role of meniscal transplantation in reducing pain and improving function in patients with prior ipsilateral meniscectomy is still being defined. HYPOTHESIS: Patients with symptomatic early-onset chondromalacia of the knee after ipsilateral meniscectomy will have improved clinical outcomes after meniscal transplantation. STUDY
DESIGN: Case series; Level of evidence, 4.
METHODS: All patients who underwent meniscal allograft transplantation between July 2003 and December 2006 were prospectively followed. The indications for surgery were unicompartmental knee pain and postactivity effusions after total or near-total meniscectomy in patients with closed physes. High-field magnetic resonance imaging (1.5-T or 3-T magnets) was used to assess the articular cartilage of the affected compartment. The meniscal transplantations were performed with an arthroscopically assisted technique. Modified Cincinnati knee and International Knee Documentation Committee (IKDC) subjective and IKDC objective outcome scores were obtained on all patients preoperatively and postoperatively to evaluate patients' outcomes.
RESULTS: Forty patients with an average age of 25 years and a body mass index of 25.4 were included. After an average final follow-up of 2.5 years, IKDC subjective scores increased significantly from 54.5 to 72.0 (P < .001). Modified Cincinnati knee scores increased from 55.2 to 75.3 (P < .001). The preoperative IKDC objective scores measuring effusion improved significantly from 6 A (normal), 29 B (nearly normal), and 5 C (abnormal), when compared with the postoperative scores of 33 A (normal) and 1 B (nearly normal) (P < .01). Five patients sustained tears of their meniscal transplants and underwent partial meniscectomies of the transplant graft.
CONCLUSION: The results confirm that meniscal transplantation significantly reduces pain, decreases activity-related effusions, and improves function in patients with prior meniscectomy; however, the long-term chondroprotective effects remain unknown.

Entities:  

Mesh:

Year:  2010        PMID: 20595551     DOI: 10.1177/0363546510368133

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  19 in total

1.  Prospective comparative study between two different fixation techniques in meniscal allograft transplantation.

Authors:  Ferran Abat; Pablo Eduardo Gelber; Juan I Erquicia; Marc Tey; Gemma Gonzalez-Lucena; Juan Carlos Monllau
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-05-03       Impact factor: 4.342

2.  Lateral meniscus allograft transplantation: an arthroscopically-assisted single-incision technique using all-inside sutures with a suture hook.

Authors:  Su-Chan Lee; Woo-Hyuk Chang; Seung-Jun Park; Tae-Ho Kim; Byung-Yoon Sung
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2013-01-18       Impact factor: 4.342

3.  Lateral Meniscal Allograft Transplantation: The Bone Trough Technique.

Authors:  Jorge Chahla; Javier Olivetto; Chase S Dean; Raphael Serra Cruz; Robert F LaPrade
Journal:  Arthrosc Tech       Date:  2016-04-18

4.  Medial Meniscal Allograft Transplantation: The Bone Plug Technique.

Authors:  Chase S Dean; Javier Olivetto; Jorge Chahla; Raphael Serra Cruz; Robert F LaPrade
Journal:  Arthrosc Tech       Date:  2016-04-04

5.  Outcome of meniscal allograft transplantation related to articular cartilage status: advanced chondral damage should not be a contraindication.

Authors:  P J Kempshall; B Parkinson; M Thomas; C Robb; H Standell; A Getgood; T Spalding
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-11-29       Impact factor: 4.342

6.  Combined osteochondral allograft and meniscal allograft transplantation: a survivorship analysis.

Authors:  Alan Getgood; Jonathon Gelber; Simon Gortz; Alison De Young; William Bugbee
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-02-12       Impact factor: 4.342

Review 7.  Meniscus repair using mesenchymal stem cells - a comprehensive review.

Authors:  Hana Yu; Adetola B Adesida; Nadr M Jomha
Journal:  Stem Cell Res Ther       Date:  2015-04-30       Impact factor: 6.832

8.  Enhanced cellular infiltration of human adipose-derived stem cells in allograft menisci using a needle-punch method.

Authors:  Rachel C Nordberg; Adisri Charoenpanich; Christopher E Vaughn; Emily H Griffith; Matthew B Fisher; Jacqueline H Cole; Jeffrey T Spang; Elizabeth G Loboa
Journal:  J Orthop Surg Res       Date:  2016-10-28       Impact factor: 2.359

Review 9.  Meniscal allograft transplantation in a symptomatic meniscal deficient knee: a systematic review.

Authors:  Nick A Smith; Nicola MacKay; Matthew Costa; Tim Spalding
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-09-14       Impact factor: 4.342

10.  The Meniscus-Deficient Knee: Biomechanics, Evaluation, and Treatment Options.

Authors:  Allison J Rao; Brandon J Erickson; Gregory L Cvetanovich; Adam B Yanke; Bernard R Bach; Brian J Cole
Journal:  Orthop J Sports Med       Date:  2015-10-23
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