Literature DB >> 20595500

Serologic and molecular characteristics of hepatitis B virus among school children in East Java, Indonesia.

Takako Utsumi1, Yoshihiko Yano, Maria Inge Lusida, Mochamad Amin, Hak Hotta, Yoshitake Hayashi.   

Abstract

Universal childhood hepatitis B vaccination was introduced in Indonesia in 1997; by 2008, coverage was estimated to be 78%. This study aimed to investigate the serologic status and virologic characteristics of hepatitis B virus (HBV) among the children in East Java. A total of 229 healthy children born during 1994-1999 were enrolled in this study. Overall, 3.1% were positive for hepatitis B surface antigen (HBsAg) and 23.6% were positive for antibody to HBsAg (anti-HBs). HBV DNA was detected in 5 of 222 HBsAg-negative carriers, which were suggested to be cases of occult HBV infection. A single amino substitution (T126I) in the S region was frequently found. HBV infection remains endemic, and the prevalence of anti-HBs remains insufficient among children in East Java, Indonesia.

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Year:  2010        PMID： 20595500      PMCID： PMC2912598          DOI： 10.4269/ajtmh.2010.09-0589

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  34 in total

1.  Adult hepatitis B vaccination using a novel triple antigen recombinant vaccine.

Authors:  M D Young; D L Schneider; A J Zuckerman; W Du; B Dickson; W C Maddrey
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Review 2.  Hepatitis B virus infection.

Authors:  W M Lee
Journal:  N Engl J Med       Date:  1997-12-11       Impact factor: 91.245

3.  Reversed passive hemagglutination test fails to detect HBsAg in a number of HBeAg positive sera.

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4.  Quantitation of hepatitis B virus genomic DNA by real-time detection PCR.

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5.  Evaluation of a new hepatitis B triple-antigen vaccine in inadequate responders to current vaccines.

Authors:  J N Zuckerman; A J Zuckerman; I Symington; W Du; A Williams; B Dickson; M D Young
Journal:  Hepatology       Date:  2001-10       Impact factor: 17.425

6.  Complete genome sequence and phylogenetic relatedness of hepatitis B virus isolates in Papua, Indonesia.

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Journal:  J Clin Microbiol       Date:  2009-04-22       Impact factor: 5.948

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Journal:  J Med Virol       Date:  2009-05       Impact factor: 2.327

Review 8.  Clinical impact of occult HBV infections.

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  15 in total

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Journal:  Am J Trop Med Hyg       Date:  2016-07-11       Impact factor: 2.345

Review 2.  Hepatitis B virus infection in Indonesia.

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4.  Ultradeep Sequencing for Detection of Quasispecies Variants in the Major Hydrophilic Region of Hepatitis B Virus in Indonesian Patients.

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Review 5.  Current hepatitis B virus infection situation in Indonesia and its genetic diversity.

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7.  Genetic Diversity of the Hepatitis B Virus Strains in Cuba: Absence of West-African Genotypes despite the Transatlantic Slave Trade.

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9.  Evaluation of adverse effects of mutein forms of recombinant human interferon alpha-2b in female swiss webster mice.

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10.  High prevalence of hepatitis B virus genotype C/C1 in the Minangkabau ethnic group in Indonesia.

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Journal:  Virol J       Date:  2013-01-22       Impact factor: 4.099
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