Literature DB >> 20595411

Treatment for PTSD related to childhood abuse: a randomized controlled trial.

Marylene Cloitre1, K Chase Stovall-McClough, Kate Nooner, Patty Zorbas, Stephanie Cherry, Christie L Jackson, Weijin Gan, Eva Petkova.   

Abstract

OBJECTIVE: Posttraumatic stress disorder (PTSD) related to childhood abuse is associated with features of affect regulation and interpersonal disturbances that substantially contribute to impairment. Existing treatments do not address these problems or the difficulties they may pose in the exploration of trauma memories, an efficacious and frequently recommended approach to resolving PTSD. The authors evaluated the benefits and risks of a treatment combining an initial preparatory phase of skills training in affect and interpersonal regulation (STAIR) followed by exposure by comparing it against two control conditions: Supportive Counseling followed by Exposure (Support/Exposure) and skills training followed by Supportive Counseling (STAIR/Support).
METHOD: Participants were women with PTSD related to childhood abuse (N=104) who were randomly assigned to the STAIR/Exposure condition, Support/Exposure condition (exposure comparator), or STAIR/Support condition (skills comparator) and assessed at posttreatment, 3 months, and 6 months.
RESULTS: The STAIR/Exposure group was more likely to achieve sustained and full PTSD remission relative to the exposure comparator, while the skills comparator condition fell in the middle (27% versus 13% versus 0%). STAIR/Exposure produced greater improvements in emotion regulation than the exposure comparator and greater improvements in interpersonal problems than both conditions. The STAIR/Exposure dropout rate was lower than the rate for the exposure comparator and similar to the rate for the skills comparator. There were significantly lower session-to-session PTSD symptoms during the exposure phase in the STAIR/Exposure condition than in the Support/Exposure condition. STAIR/Exposure was associated with fewer cases of PTSD worsening relative to both of the other two conditions.
CONCLUSIONS: For a PTSD population with chronic and early-life trauma, a phase-based skills-to-exposure treatment was associated with greater benefits and fewer adverse effects than treatments that excluded either skills training or exposure.

Entities:  

Mesh:

Year:  2010        PMID: 20595411     DOI: 10.1176/appi.ajp.2010.09081247

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  124 in total

1.  Cognitive behavioral therapy for posttraumatic stress disorder in individuals with severe mental illness and borderline personality disorder.

Authors:  M Alexandra Kredlow; Kristin L Szuhany; Stephen Lo; Haiyi Xie; Jennifer D Gottlieb; Stanley D Rosenberg; Kim T Mueser
Journal:  Psychiatry Res       Date:  2017-01-04       Impact factor: 3.222

2.  Challenges and Successes in Dissemination of Evidence-Based Treatments for Posttraumatic Stress: Lessons Learned From Prolonged Exposure Therapy for PTSD.

Authors:  Edna B Foa; Seth J Gillihan; Richard A Bryant
Journal:  Psychol Sci Public Interest       Date:  2013-05

3.  Pre-treatment predictors of dropout from prolonged exposure therapy in patients with chronic posttraumatic stress disorder and comorbid substance use disorders.

Authors:  Emily L Belleau; Eu Gene Chin; Sonya G Wanklyn; Laura Zambrano-Vazquez; Julie A Schumacher; Scott F Coffey
Journal:  Behav Res Ther       Date:  2017-01-25

4.  A Quasi-experimental outcomes analysis of a psychoeducation intervention for pregnant women with abuse-related posttraumatic stress.

Authors:  Heather Rowe; Mickey Sperlich; Heather Cameron; Julia Seng
Journal:  J Obstet Gynecol Neonatal Nurs       Date:  2014-04-22

5.  Prospective risk factors for adolescent PTSD: sources of differential exposure and differential vulnerability.

Authors:  Stephanie Milan; Kate Zona; Jenna Acker; Viana Turcios-Cotto
Journal:  J Abnorm Child Psychol       Date:  2013-02

6.  Definition, assessment and rate of psychotherapy side effects.

Authors:  Michael Linden; Marie-Luise Schermuly-Haupt
Journal:  World Psychiatry       Date:  2014-10       Impact factor: 49.548

7.  The Range of Psychotherapies for PTSD.

Authors:  John C Markowitz
Journal:  Am J Psychiatry       Date:  2018-10-01       Impact factor: 18.112

8.  Heterogeneity in the Strength of the Relation Between Social Support and Post-Trauma Psychopathology.

Authors:  Matthew Price; Sarah Pallito; Alison C Legrand
Journal:  J Psychopathol Behav Assess       Date:  2017-10-03

Review 9.  Post-traumatic stress disorder and cardiometabolic disease: improving causal inference to inform practice.

Authors:  K C Koenen; J A Sumner; P Gilsanz; M M Glymour; A Ratanatharathorn; E B Rimm; A L Roberts; A Winning; L D Kubzansky
Journal:  Psychol Med       Date:  2016-10-04       Impact factor: 7.723

10.  Emotion regulation difficulties as a prospective predictor of posttraumatic stress symptoms following a mass shooting.

Authors:  Joseph R Bardeen; Mandy J Kumpula; Holly K Orcutt
Journal:  J Anxiety Disord       Date:  2013-02-13
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.