| Literature DB >> 20593838 |
Bing-Dong Lin1, Mei-Ling Han, Yin-Chun Ji, Hua-Dong Chen, Sheng-Ping Yang, Sheng Zhang, Mei-Yu Geng, Jian-Min Yue.
Abstract
Six new oxygenated daphnane-type diterpenoids, trigoxyphins A-F (1-6), a phenanthrene-type diterpenoid, trigoxyphin G (7), and two known compounds were isolated from twigs of Trigonostemon xyphophylloides. Their structures were established using spectroscopic methods. Compounds 1 and 2 exhibited strong cytotoxic activity against HL60 (IC(50): 0.27 and 0.49 microM) and A549 (IC(50): 7.5 and 4.9 microM) tumor cell lines, respectively.Entities:
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Year: 2010 PMID： 20593838 DOI： 10.1021/np100320h
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050