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Literature DB >> 20593090

1,10-Phenanthroline platinum(II) complex: a simple molecule for efficient G-quadruplex stabilization.

Jin-Tao Wang¹, Xiao-Hui Zheng, Qing Xia, Zong-Wan Mao, Liang-Nian Ji, Kui Wang.

Abstract

Two simple complexes [Pt(phen)(2)](PF(6))(2) and [Pt(bpy)(2)](PF(6))(2) exhibit high stabilization potential for G-quadruplex DNA with [Pt(phen)(2)](PF(6))(2) possessing higher capability due to its greater planarity.

Entities: Chemical

Mesh：

Substances：

Year: 2010 PMID： 20593090 DOI： 10.1039/c0dt00211a

Source DB: PubMed Journal: Dalton Trans ISSN： 1477-9226 Impact factor: 4.390

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Cited

6 in total

1. Copper(ii) l/d-valine-(1,10-phen) complexes target human telomeric G-quadruplex motifs and promote site-specific DNA cleavage and cellular cytotoxicity.

Authors: Farukh Arjmand; Surbhi Sharma; Sabiha Parveen; Loic Toupet; Zhen Yu; James Allan Cowan
Journal: Dalton Trans Date: 2020-07-21 Impact factor: 4.390

2. A Nitroxide-Tagged Platinum(II) Complex Enables the Identification of DNA G-Quadruplex Binding Mode.

Authors: Cui-Xia Xu; Xiaojun Zhang; Yi-Wei Zhou; Hanqiang Wang; Qian Cao; Yong Shen; Liang-Nian Ji; Zong-Wan Mao; Peter Z Qin
Journal: Chemistry Date: 2016-02-04 Impact factor: 5.236

3. V-shaped dinuclear Pt(II) complexes: selective interaction with human telomeric G-quadruplex and significant inhibition towards telomerase.

Authors: Cui-Xia Xu; Yu-Xuan Zheng; Xiao-Hui Zheng; Qian Hu; Yong Zhao; Liang-Nian Ji; Zong-Wan Mao
Journal: Sci Rep Date: 2013 Impact factor: 4.379

1,10-Phenanthroline platinum(II) complex: a simple molecule for efficient G-quadruplex stabilization.

1. Copper(ii) l/d-valine-(1,10-phen) complexes target human telomeric G-quadruplex motifs and promote site-specific DNA cleavage and cellular cytotoxicity.

2. A Nitroxide-Tagged Platinum(II) Complex Enables the Identification of DNA G-Quadruplex Binding Mode.

3. V-shaped dinuclear Pt(II) complexes: selective interaction with human telomeric G-quadruplex and significant inhibition towards telomerase.

4. G-quadruplex structural transition driven by a platinum compound.

5. A Water-Soluble Tetraazaperopyrene Dye as Strong G-Quadruplex DNA Binder.

Review 6. Metal-Based G-Quadruplex Binders for Cancer Theranostics.